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| Melatonin acts synergistically with pazopanib against renal cell carcinoma cells through p38 mitogen-activated protein kinase-mediated mitochondrial and autophagic apoptosis |
| Chien-Pin Lai, Yong-Syuan Chen, Tsung-Ho Ying, Cheng-Yen Kao, Hui-Ling Chiou, Shao-Hsuan Kao, Yi-Hsien Hsieh |
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Kidney Res Clin Pract. 2023;42(4):487-500. Published online May 4, 2023 DOI: https://doi.org/10.23876/j.krcp.22.114 |
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Melatonin acts synergistically with pazopanib against renal cell carcinoma cells through p38 mitogen-activated protein kinase-mediated mitochondrial and autophagic apoptosis Kidney Research and Clinical Practice. 2023;42(4):487-500  Activation of p38 mitogen-activated protein kinase is critical step for acquisition of effector function in cytokine-activated T cells, but acts as a negative regulator in T cells activated through the T-cell receptor Immunology. 2010;132(1):104-110 Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade Apoptosis. 2008;13(12):1450-1464 Ghrelin protects against depleted uranium-induced apoptosis of MC3T3-E1 cells through oxidative stress-mediated p38-mitogen-activated protein kinase pathway Toxicology and Applied Pharmacology. 2016;290:116-125 Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor Cellular Signalling. 2006;18(9):1447-1454 Honokiol causes the p21WAF1-mediated G(1)-phase arrest of the cell cycle through inducing p38 mitogen activated protein kinase in vascular smooth muscle cells FEBS Letters. 2006;580(22):5177-5184 Isoflavone genistein protects human vascular endothelial cells against tumor necrosis factor-α-induced apoptosis through the p38β mitogen-activated protein kinase Apoptosis. 2008;14(1):66-76 Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway Breast Cancer Research. 2010;12(6): 1965 OXALATE INDUCED P38 MITOGEN ACTIVATED PROTEIN KINASE ACTIVATION IS MEDIATED BY MITOGEN ACTIVATED PROTEIN KINASE KINASE-6 (MKK6) IN HK-2 CELLS, A LINE OF HUMAN KIDNEY EPITHELIAL CELLS Journal of Urology. 2010;183(4S): Daphnetin induced differentiation of human renal carcinoma cells and its mediation by p38 mitogen-activated protein kinase Biochemical Pharmacology. 2004;67(9):1779-1788 |
