Korean Journal of Nephrology 1985;4(2):218-223.
특발성 IgA 신병증에 대한 임상적 고찰
윤정한 , 이호영 , 하성규 , 김도영 , 주현영 , 한대석
Abstract
We reviewed the clinical features and laboratory findings of 29 cases of idiopathic IgA nephropathy and the following results were obtained; 1) This study included 29 cases in which 15 cases were male and 14 cases were female showing no sexual predisposition. Gross hematuria was the most prevalent symptom presented by 12 cases (41. 4%), of which 9 cases had upper respiratory infection. Admission due to asymptomatic protei- nuria and microscopic hematuria were 11 cases(3 7. 9%%); mild edema, 5 cases(17. 2%); lumbago, 2 cases(6.8%), and 3 cases(10.3%.) of which had hypertension. 2) On urinalysis, microscopic hematuria was detected in all cases and proteinuria of more than 1(+) was detected in 26(89.7%) cases(89.7%). Eleven cases(37. 9%) had 24 hour urine protein below 5po mg; 8 cases (27. 6%), 500-1, 000 mg; 4 cases (13. 8%), 1, 000-2, 000mg; 2 cases (6. 9%), 2, 000-3, 000 mg and urinary protein above 3, 000 mg were observed in 4 cases(13.8%). 3) Average serum CR level was 77. 7 mg/dl. 4) Mean serum IgA level was 301mg/dl in 19 cases of which 4 cases showed a level exceeding 350 mg/dl. 5) Creatinine clearance was performed in 19 cases of which 12 cases(6.1%) had values above gp ml/min/l. 73 m, 5 cases(26. 3%Yo), 60-90 ml/ min/1.73m, 1 case(5.3%), 30-60ml/min/1.73 m, and 1 case(5 3%), below 30 ml/min/1 .73 m. 6) Follow up studies were available in 2] cases with average of 9 .7months ranging from 1 to Rl months. There were no changes in renal function among studied cases.
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