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| IgA Nephropathy에 대한 임상적 연구 |
| 최은영 , 유관희 , 안중기 , 강성귀 |
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| Abstract |
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IgA nephropathy has been recognized as a distinct form of primary glomerulonephritis since its initial description by Berger in 1968. Its cha- racteristic feature is the diffuse glomerular depo- sition of immunoglobulin A as the predominant protein. There is no associated with systemic disease. Forty-one cases of the IgA nephropathy were studied clinically at the Chonbuk National Unive- rsity Hospital during the period of 4 years, from January, 1982 to Febuary, 1986. The patients average age was 30±13. 3 year, between 15 and 67 years of age and the ratio of male(26) to female(15) was l. 7 to l. On admission gross hematuria cases were 22 (54%), mild facial edema, fatigue, flank pain, headache, upper respiratory infection in frequen- cy. The patterns of hematuria were recurrent gross hematuria 18(44%), recurrent microscopic type 14(34%), single gross hematuria 5(12%) and single microscopic type 4(10%,), respectively. The serum IgA level was increased in 27%. In percutaneous renal biopsy, mesangial and glomerular lesion were 92. 9% and tubular lesion 35.7% In immunofluorescent study, IgA,G,M, C, and fibrin deposition was 100%. We was done follow up average 15 months ranging from one month to 5 years, and 2 patients were progressed to nephrotic syndrome, one case were developed transiently acute renal failure but recovered. Other patients were no changes renal function yet. |
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