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| Paraquat poisoning에서의 hemoperfusion 치료 경험 |
| 김시환 , 최재성 , 윤경우 , 김영조 , 최수봉 , 김종설 |
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| Abstract |
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Para quat is a widely used herbicide and its in-gestion induces acute renal failure, hepatic dys- function and progressive respiratory failure with high mortality rate. Charcoal hemoperfusion has been used in the treatment of various poisoning including paraquat since 1948, but it has not been reported yet in Korea. So we report charcoal hemoperfusion in a case of paraquat poisoning with review of litera- ture. The present case was a 14-year-old female who was admitted due to dysphagia and epigastric pain. The above mentioned chief complaints occurred 6 days prior to admission when she ingested para- quat with suicidal attempt. She was treated with 4 times of charcoal hemo- perfusion using Gambro Adsorba 150C in addition to conventional treatment and achieved favorable progress in both clinical and laboratory examina- tion. Up to 7 Iilonths after paraquat poisoning she was free of any complication so we presume that she vras completely recovered from the deleterious effect of paraquat. Hemoperfusion is a safe, effective and simple method of treating severe poisoning and it seems to be of particular value in paraquat poisoning because it is endemic in Korea and no specific treatment is available in paraquat poisoning. We suggest that measurement of various serum drug Ievel should be available and further evalua- tion of hemoperfusion in various disease states are necessary. |
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