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당뇨병 CAPD 환자의 Insulin치료 |
이시래 , 최창필 |
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Abstract |
Over the years results with all types of treatment have progressively improved, which allows for encourgement and optimism. CAPD is increasingly used not only because of econornic advantages but also the improved clinical and metabolic results. An excellent control of blood glucose level is made possible by using the intraperitoneal route three to four times a day for administration of insulin. Since the insulin delivered intraperitoneally in absorbed from the peritoneal cavity via the hepatic portal system which is the site of entry for pancreatic insulin, it seem likely that this would be a "physiologic" delivery route. Because of certain simi- larties between physiological insulin secretion and intra- peritoneal insulin administration, it is expected that the intraperitoneal administration of insulin during CAPD will give excellent diabetic control and achieve more desirable long term results in diabetic end stage renal disease. We reviewed some authors articles for the administration of insulin in diabetics during CAPD and shared our experiences in this article. During the last 4 years, we have treated 17 diabetics with CAPD. Good control of blood sugar was achieved by intraperitoneal administration of insulin. Average period required to control blood sugar was 13 days. After our patients blood sugar was stablized, their daily average insulin requirement was 46 units, ranged from 8 to 162 units. |
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