Korean Journal of Nephrology 1988;7(1):174-181.

압박 증후군을 동반하그런데 급성 신부전 3예

홍관수 , 이일중 , 김동욱 , 김영균 , 윤영석 , 방병기

Abstract

We studied the characteristic clinical findings and the effect of dialysis therapy in 3 cases of hypercatabolic acute renal failure associated with muscle compartment syndrome which was induced by overnight muscle com- pression after drug abuse (phenobarbital, case 1) and carbon monoxide intoxication (case 2,3). The major symptoms of muscle compartment syn- drome in this cases were generalized muscle swelling with extreme tenderness, hypoesthesia, paralysis and aching pain with pallor and coldness in involved limb. Acute renal failrue was characterized by almost anuric hypercatabolic state, red brownish urine without RBC (myoglobinuria) and rapid increase of blood urea nitro- gen. They were treated with immediate dialysis therapy including CAPD, intensive hemodialysis and combined dialysis. Renal functions were all returned to normal eventually, but uremic symptoms and the increase rate of blood urea nitrogen was less severe in intensive hemodialysis cases as compared with CAPD cases (Fig. We studied the characteristic clinical findings and the effect of dialysis therapy in 3 cases of hypercatabolic acute renal failure associated with muscle compartment syndrome which was induced by overnight muscle com- pression after drug abuse (phenobarbital, case 1) and carbon monoxide intoxication (case 2,3). The major symptoms of muscle compartment syn- drome in this cases were generalized muscle swelling with extreme tenderness, hypoesthesia, paralysis and aching pain with pallor and coldness in involved limb. Acute renal failrue was characterized by almost anuric hypercatabolic state, red brownish urine without RBC (myoglobinuria) and rapid increase of blood urea nitro- gen. They were treated with immediate dialysis therapy including CAPD, intensive hemodialysis and combined dialysis. Renal functions were all returned to normal eventually, but uremic symptoms and the increase rate of blood urea nitrogen was less severe in intensive hemodialysis cases as compared with CAPD cases (Fig.)