Korean Journal of Nephrology 1989;8(3):504-510.
성인중추성 요붕증에 Chlorpropamide 및 Indomethacin 의 효과
이승호 , 박영규 , 김정권 , 장현철 , 박성광 , 강성귀
Abstract
Although administration of Chlorpropamide on 26 year-old female diabetes insipidus patient caused signifi- cant decrease in urine volume and increase of urine osmolality, combined administration with indomethacin did not increase the chlorpropamide effect. However, combined administration of chlorpropamide and indomethacin on 45 year-oid male diabetes insipidus patient seemed to produce much lower urine volume. Since the results vary, the antidiuretic effect of in- domethacin can be concluded after experiencing more cases.
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