Korean Journal of Nephrology 1990;9(4):477-484.

말기 신부전증 환자에서 후천성 신 낭성 변화

최규복 , 윤견일 , 고은주 , 서정수

Abstract

To evaluate the incidence and clinical characteristics of ACKD (Acquired Cystic Kidney Disease), we measur- ed several clinical variables and performed abdominal computerized tomographic scanning in 18 patients with end-stage renal disease. The results were as follows; 1) Among 18 end-stage renal failure patients with maintenance dialysis, male were 6 and female were 12 in number. The mean age and mean time on dialysis were 40 years/24 months in male patients and 38 years/36 months in female patients. 2) ACKD was found in three(17%) of 18 and suspicious ACKD was found in two(11%) of 18. If any detectable cysts are sufficient, then five (28%) of 18 had ACKD. 3) The mean time on dialysis were 39 months in ACKD, 58 months in suspicious ACKD and 25 months in patients witout cyst. 4) In 11 patients who were dialyzed for less than 4 years, only one (9%) had ACKD, but another ten (91%) had no cyst. In 7 patients who were dialyzed for more than 4 years, two (29%) had suspicious ACKD, another two (295) had ACKD and the other three (43%) had no cyst. 5) In 6 male patients, three (50%) had no cyst, another two (33%) had ACKD and the other one (17%) had suspicious ACKD. In 12 female patients, ten (83%) had no cyst, another one (8%) had ACKD and the other one (8%) had suspicious ACKD. 6) The largest size of cyst in each case of ACKD ranged from 0.7 cm to 2.4 cm in diameter. 7) The mean length of kidney in right and left were as follows: in patients without cyst, 6.3/5.9 cm; in patients with suspicious ACKD, 6.5/4.8 cm; in patients with ACKD, 7.5/7.8 cm. 8) The mean hematocrit were 19% in patients without cyst, 20% in patients with suspicious ACKD and 27% in patients with ACKD. From the above data, we knew that a prolonged period of dialysis increased the incidence of ACKD, and male had a higher incidence of ACKD than female. Also we knew that the kidney size and hematocrit were increased in ACKD.