Korean Journal of Nephrology 1992;11(4):477-481.
급성신부전을 동반한 발작성 야간혈색소뇨증 2예
김선숙 , 이영호 , 연종은 , 안정천 , 신상원 , 차대룡 , 권영주 , 조원용 , 김준석 , 김형규 , 원남희
Abstract
Paroxysmal nocturnal hemoglobinuria is an uncom- mon acquired disease of unknown etiology character- ized by recurrent chronic hemolytic anemia and throm- bosis. Rarely acute renal failure may occur. The path- ogenesis of acute renal failure in PNH is not well understood. We experienced two cases, which were shown acute renal failure and hemolytic anemia as first manifesta- tion and then diagnosed as PNH by Hams test. These patients might be progressed acute renal failure by hemolytic crisis associated with aggravating factors such as dehydration, hypotension, and renal ischemia.
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