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전신성 홍반성 낭창에 동반된 제 4형 신세뇨관 산혈증 1예 |
정해억 , 박지원 , 김승준 , 진동찬 , 최영진 , 김용수 , 윤영석 , 방병기 |
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Abstract |
In systemic lupus erythematosus, type 4 renal tubular acidosis is often occurred by diffuse immune-comlex deposit in the interstitial tissue and juxtaglomerular apparatus. A 25-year-old male patient with complaint of generalized edema, easy fatigability, alopecia and arthralgia for 1 month, he was diagnosed as systemic lupus erythematosus and diffuse proliferative lupus nephritis through the serologic, immunologic test and renal biopsy. Simultaneously hyperkalemia, hyperchloremia, metabolic acidosis with normal anion gap was detected but his renal function was normal. With the bicarbonate loading test and basal and stimulated plasma renin, aldosterone level, he was diagnosed as type 4 renal tubular acidosis caused by hyporeninemic hypoaldosteronism. We report this case as type 4 renal tubular acidosis associated with systemic lupus erythematosus with review of literature. |
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