Korean Journal of Nephrology 1993;12(4):621-625.

한국 소아의 뇨 칼슘 배설 - 1. 집단 선별검사를 위한 무작위 뇨 칼슘 / 크레아닌 비 - (Urinary Calcium Excretion of Korea Children - 1. Ratio of Calcium and Creatinine in Random Urine -)

이재승 , 노혜옥 ( Jae Seung Lee , Hye OK Roh )

Abstract

Hypercalciruia must be diagnosed early and treated adequately since it is an important cause of hematuria and ureter stone and also because it may damage the renal tubules irreversibly and decrease the coacentra tion ability of urine. Until now in Korea, there has been only a small number of reports and no useful standards on calciuria. Our study was done to find the normal value of the ratio of calcium and to find the normal value of the ratio of calcium and creatinine in random urine of Korean children. We studied 464 children in the pediatric department of the %nsei University hospital who had normal serum calcium levels and no renal and endocrine disease or calcium metabolic abnormalities. Urine collection was done using disposable urine collector for children under 3 years of age, and urine cup for children over 3 years of age. Urine sodium, creatinine and calcium were evaluated. Analysis was done by PC-SPSS to assess the mean+-SD of each age and the differences of each group was compared using t-test. The results were as follows. Ca/Cr ratio was 0 05+-0 09(mean+-SDmg/dl) in 0-7d, 0 28+-0 24 in 8-30d, 0 22+- 0 21 in l-ll mo, 0 20?0 19 in 1-5 yr, 0, 17+-0 19 in 6-11 yr and 0 12+-0 09 in 12-15 yr group. Comparing ratio in each age group. 0-7d and 12-15 yr group showed a difference compared to other groups (p < 0 05). In conclusion, the Ca/Cr ratio in random urine of Korean children showed a difference between the 0-7 d, 12 -15 yr and other age groups, The normal value of 0-7 d group is 0 05+-0 09 and 12-15 yr group is 0 12+-0 09. The other groups were 0 20+-0 20 mg/dl.