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| 비호지킨 림프종에 병발된 한랭글로브린 혈증가 사구체신염 1예 |
| 정해혁 , 서동완 , 최정은 , 강재영 , 장재원 , 박수길 , 이인철 , 지현숙 |
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| Abstract |
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A case of glomerulolnephritis associated with non- Hodgkins lymphoma are described. The patient pres- ented with purpura, nephrotic syndrome and impaired renal function. The patient had cryoglobulinemia with rheumatoid factor activity, hypocomplementemia, and anti-HCV antibody, and charaterization of the cryoglobulin revealed the presence of a monoclonal IgM kappa component together with polyclonal IgG, Skin biopsy and renal biopsy revealed a leukocytoclastic vasculitis and a typial cryoglobulinemic nephropathy: diffuse proliferative glomerulonephritis with monocyte infiltration and subendothelial deposition of IgM, IgG, IgA, and C3. Bone marrow biopsy revealed a small lympholcytic lymphoma: monotonous small sized neoplastic lymphoid cell infiltration. The vasculitis, nephrotic syndrome, and renal function were improved after lymphoma treatment with chemotheraphy. |
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