Korean Journal of Nephrology 1996;15(2):204-208.
신증후성 출혈열에 속박된 범 뇌하수체 기능 저하증 및 중추성 뇨붕증 1예
이흥범 , 임석태 , 이진희 , 박성광 , 백홍선 , 강성귀
Abstract
The clinical course of HFRS may be divided into five phases on the basis of the underlying physio- logic aberrations ' febrile, hypotensive, oliguric, diuretic, and convalescent. But there is a considerable variation among patients in the severity of the illness, and generally, HFRS has a benign course though fatal cases and severe complications have been reported such as panhypopituitarism. We experienced a case of panhypopituitarism with cen- tral diabetes insipidus on convalescent phase of HFRS. This 61-year female patient was diagnosed HFRS by history, clinical symptoms, and serologic titer to Hantaan virus. On progression, She com- plained weakness, polyuria above 5L per day, and polydypsia. We examined the level of pituitary hormons and water deprivation test. Those results suggested panhypopituitarism and central diabetes insipidus. After hormone replacement, she felt well and discharged. And now, we report the case with review.
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