Korean Journal of Nephrology 1997;16(2):369-373.
위암수술을 받은 젊은 성인에서 발생한 Henoch - Schonlein 자반증과 이에 동반된 자발성 세균성 복막염 1예
김용섭 , 김형규 , 원남희
Abstract
Henoch-Schonlein purpura(HSP) occurs frequently in childhood and is a few occurrence in adults. The occurrence of nephrotic syndrome is rare in HSP patients and the association of renal disease with HSP is very important to prospect longterm clinical outcome. The causes of HSP have been diversely reported such as foods, drugs, sensitivity to infections, vacci- nation, insect bite, cold exposure etc and recently immune complex is studing as representative cause of HSP, but nothing is verified of definite mech- anism of HSP until now. The occurrence of HSP associated with cancer has been rarely reported in the literature but there is no report in Korea. The patient was 31 year-old woman with sto- mach cancer who was operated in our hospital. 5 months after operation of stomach cancer, the massive proteinuria, generalized edema were deve- loped and thereafter abdominal pain, generalized purpuric lesion on extremities were also occurred. We have done kidney biopsy and biopsy findings were compatible with HSP pathologically. After administration of prednisolone, spontaneous bacterial peritonitis was occurred sudderily, patient was recovered after ceasation of administration of prednisolone and proper antibiotic therapy but patient died of cachexia 3 months after diagnosis of HSP. We report a case of HSP presenting as nephrotic syndrome in patient with stomach cancer and complicated with spontaneous bacterial peritonitis.
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