Korean Journal of Nephrology 1998;17(6):905-910.

영아와 1세 이상 소아의 방광요관 역류의 임상적 비교분석 (Clinical Comparison of Vesicoureteral Reflux in Infants and Children more than 1 Year Old)

이상돈, 손동완, 정문기 (Sang Don Lee, Dong Wan Sohn and Moon Kee Chung)

Abstract

Purpose
We performed a retrospective study to determine the comparative characteristics of vesicoureteral reflux(VUR) between the infants less than 1 year and children more than 1 year old and whether early treatment in infantile VUR may be of benefit to preserve the renal function and to prevent the new renal scar. Materials and Methods:All of 62 cases(infant group 19 and children group 43) with primary VUR were managed as the ureteral reimplantation from January 1991 to December 1996. Results:The average age of patients was 7.1 months in infant group and 6.0 years in children group. The sex ratio of male to female showed no difference between infant and children group(1.7:1 Vs 1.5:1). The average follow up periods were 20.5 and 23.7 months in infant and children groups, respectively. The high grade reflux and renal scarring in infant group were significantly more frequent than those in children group(P<0.05), but the prevalence of urinary tract infection in children group was significantly higher than that in infant group(P<0.05). There was no significant difference in the rates of bilaterality and in the sex ratio between infant and children group. The success rate of operation was 100 percent in both groups. Conclusion:We suggest that the early surgical treatment in infants with bilateral and higher grade VUR may be of benefit to the preservation of renal function and the decrease of renal parenchymal change.