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| 신증후 출혈열 환자에서 Soluble Intercellular Adhesion Molecule-1의 변화 (The Change of Soluble Intercellular Adhesion Molecule-1 Levels in Hemorrhagic Fever with Renal Syndrome) |
| 송호철, 박철휘, 양철우, 박정희, 박주현, 김병수, 김영옥, 김석영, 최의진, 장윤식, 방병기 (Ho Cheol Song, Chul Hee Park, Chul Woo Yang, Jung Hee Park, Young Ok Kim, Suk Young Kim, Euy Jin Choi, Yoon Sik Chang, Byung Kee Bang, Yoo Hyun Park and Byung Su Kim) |
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| Abstract |
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The serum levels of sICAM-1 were significantly higher in febrile & hypotensive(789±241ng/ml) stage than in diuretic stage(514±151ng/ml) and convalescence stage(410±88ng/ml)(P<0.01). Also the serum levels of sICAM-1 in oliguric(628±220ng/ml) stage higher than that of convalescence stage(P<0.01). The serum level of sICAM-1 was significantly high in convalescence stage of patients with HFRS compared to control(306±75ng/ml)(P<0.01). sICAM-1 levels correlated with platelet count(R=-0.35, P<0.05) in all stage of HFRS. Our results suggest that the enhanced immune activation is a common feature in early stage of HFRS. |
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