Korean Journal of Nephrology 2000;19(6):1086-1090.
만성 신부전증 환자의 중증 고혈당에 따른 의식변화 결핍에 대한 연구 (Study for the Lack of Mental Changes to Severe Hyperglycemia in Diabetic Patients with Renal Failure)
위형중(Hyung Joong We) , 이창범(Chang Bum Lee) , 박성광(Sung Gwang Park) , 강성귀 , 임천규(Chun Gyu Lim) , 박은주(Eun Joo Park) , 윤경택(Gyoung Taek Yoon) , 한상웅(Sang Woong Han) , 안유헌(Yoo Hun An) , 김호중(Ho Joong Kim)
Abstract
In diabetic patients who were being treated with hemodialysis, coma and other neurological deficits did not occur in spite of extremely elevated serum glucose levels. In this report, we compared diabetic patients with renal failure in severe hyperglycemia with nonketotic hyperosmolar coma patients with normal renal function to know what affect mental changes. Mental changes were not present in diabetic patients with renal failure. These patients with renal failure showed more severe hyperglycemia, but corrected serum sodium concentration and calculated effective serum osmolality were low. So it is suggested that corrected serum sodium concentration and effective serum osmolality are more important factor affecting mental changes than high blood glucose levels in diabetic patients with renal failure, due to absence of osmotic diuresis.
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