Korean Journal of Nephrology 2001;20(4):714-718.
증례 : 신성 저뇨산형증 환자에서 운동 후 발생한 급성 신부전증 1 예 (Case Reports : Exercise - induced Acute Renal Failure in a Patient with Renal Hypouricemia)
김명재(Myung Jae Kim),장현하(Hyun Ha Chang),김희진(Hee Jin Kim),이재진(Jae Jin Lee),김진혁(Jin Hyuk Kim),이태원(Tae Won Lee),임천규(Chun Gyoo Ihm)
Abstract
We report a case of exercise-induced acute renal failure associated with renal hypouricemia in a 35- year-old man who complained of oliguria and back pain after swimming. Laboratory tests revealed that serum blood urea nitrogen and creatinine level were elevated, the serum uric acid concentration was sub- normal(2.1 mg/dL). After conservative treatment, renal function was recovered. But, uric acid level decreased to 0.4 mg/dL. In addition, there was no supression of urate clearance to creatinine clearnace ratio(CUA/Ccr) following the administration of pyrazinamide, and no increase of CUA/Ccr, after benzbromarone. Therefore, we think the cause of renal hypouricemia in this patient may be the subtotal defect in the urate transport.
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