Korean Journal of Nephrology 2007;26(5):630-633.
A Case of IgA Nephropathy Associated with Leptospirosis
Ho Sik Shin, M.D.1, Sang Eun Lee, M.D.1 , Sei Won Lee, M.D.1, Byung Ha Chung, M.D.1 Tae Jun Hwang, M.D.1 and Jin Ho Kwak, M.D.2
Department of Internal Medicine1
The Armed Forces Yangju Hospital, Gyeonggi Province Department of Internal Medicine2
School of Medicine, Catholic University of Daegu, Korea
렙토스피라증에 동반된 IgA 신병증 1예
신호식1 이상은1 이세원1 정병하1 황태준1 곽진호2
국군양주병원 내과1, 대구가톨릭대학교 의과대학 내과학교실2
Abstract
Leptospirosis is a spirochaetal infectious disease caused by Leptospira interrogans. Multiple organ involvement may be encountered in leptospirosis. Early renal involvement is very common and aracterized by tubulo-interstitial nephritis and tubular dysfunction. Rarely, diffuse mesangial proliferative glomerulonephritis may be seen. Immunoglobulin A nephropathy (IgA nephropathy) is defined by the predominant deposition of IgA in the glomerular mesangium. The secondary IgA nephropathy is thought to be caused by hepatobiliary disease, mucosal disease, infection, malignancy, some hematologic disease and systemic autoimmune or hypersensitivity disease. However, there are few reports about IgA nephropathy associated with leptospirosis. We herein report a case of IgA nephropathy in 21-yearold leptospirosis patient.


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