Korean Journal of Nephrology 2008;27(2):211-219.
Change of Body Composition Analyzed by Bioelectrical Impedance Analysis (BIA) in Renal Transplant Recipients
In-Kyong Hur, M.D., Eun-Young Lee, M.D., Ji-Hyung Cho, M.D., Ji-Young Choi, M.D.,Jung-Joo Seo, M.S., Sun-Hee Park, M.D., Chan-Duck Kim, M.D. and Yong-Lim Kim, M.D.
Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea
원저 : 생체전기 임피던스 분석기를 이용한 신이식 후 체수분 분포의 변화
허인경·이은영·조지형·최지영·서정주·박선희·김찬덕·김용림
경북대학교 의과대학 내과학교실
Abstract
Purpose
: To investigate the changes of body fluid status after kidney transplantation (KT) and to find out the associated factors.
Methods
: Forty-five patients who had received KT were classified into hemodialysis (n=32), peritoneal dialysis (n=5), and preemptive (n=8) groups by dialysis modality. %TBW, %ECF, %ICF, and edema index which were examined by bioelectrical impedance analysis as well as clinical parameters were prospectively measured before KT and 1st month, 3rd month, 6th month after KT.
Results
: Before KT, there were no significant differences in all of the parameters listed above among the three groups. Mean %TBW and %ICF were not different compared to those of before KT. In contrast, mean %ECF markedly decreased within 1st month (before KT 21.13±3.04 L/kg, 1st month 20.03 ±2.37 L/kg, 3rd month 19.61±2.18 L/kg, 6th month 18.32±5.02 L/kg: p=0.007, p<0.001, p=0.001, respectively). Edema index also decreased from 1st month (1st month 0.354±0.014, 3rd month 0.352 ±0.011, 6th month 0.348±0.014: p=0.016, p=0.012, respectively). Only edema index was higher at 1st and 3rd month in hemodialysis group. Serum creatinine and 24 hour urine total protein were positively correlated with %ECF at 1st and 3rd month, and with %TBW at 3rd month.
Conclusion
: The recovery of body water distribution after KT starts with reduction of ECF within the 1st month. Serum creatinine and proteinuria are related to the recovery. No significant difference according to dialysis modality was found. Further study with larger sample size is necessary to confirm these findings.
Key Words: Electric impedance, Extracellular fluid, Kidney transplantation


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