A Case of Primary Hepatic Angiosarcoma after Renal Transplantation

Korean Journal of Nephrology 2008;27(2):264-269.

Junshik Hong, M.D.1, Jae Chan Park, M.D.1 , Young Sil Eom, M.D.1, Minjung Kim, M.D.2, Sanghui Park, M.D.2, Woo Kyung Chung, M.D.1, Yeon Ho Park, M.D.3, Jaeseok Yang, M.D.1 and Hyun Hee Lee, M.D.1

Department of Internal Medicine¹
Department of Pathology²
Department of Surgery³
Gachon University of Medicine and Science, Incheon, Korea

증례 : 신장이식 후 발생한 원발성 간 혈관육종 1예

홍준식1, 박재찬1, 엄영실1, 김민정2, 박상희2, 정우경1, 박연호3, 양재석1, 이현희1

가천의과학대학교 내과학교실1, 병리학교실2, 외과학교실3

Abstract

Malignancy is one of the important complications after renal transplantation, and decreases both patient survival and graft survival. Hepatic angiosarcoma is the most common sarcoma in liver, but a rare malignant tumor which occupies about 2% of all hepatic malignancies. We report a case of primary hepatic angiosarcoma after renal transplantation, the first case of post-transplantation angiosarcoma in Korea. A 27-year old man had received a living related renal transplantation. He was admitted due to clinical manifestations of liver cirrhosis such as ascites, spontaneous bacterial peritonitis, and varix bleeding at 8 months after transplantation. Whole liver was infiltrated with angiosarcoma; therefore, he was managed only by supportive care. Considering the poor prognosis of hepatic angiosarcoma, both careful screening of malignancy before transplantation and periodic surveillance of malignancy after transplantation are essential.

Key Words: Hemangiosarcoma, Kidney transplantation, Neoplasms