| Contrast-induced Nephropathy in Patients Undergoing Percutaneous Coronary Angiography and its Clinical Characteristics |
| Won Choi, M.D.1, Hyun-Min Lim, M.D.2 , Hye Jin Won, M.D.2 Hye Kyeong Park, M.D.2, Ban Suck Lee, M.D.2, Hyo Seung Ahn, M.D.2 Hye-Won Joo, M.D.2, Sang Hyun Kim, M.D.2 and Won Do Park, M.D2. |
| Department of Internal Medicine, Il-gok Hospital1 Sanggye Paik Hospital, College of Medicine, Inje University2 |
| 원저 : 관상동맥 조영술을 시행한 환자에서 조영제 신독성 발생에 관한 임상연구 |
| 최 원1•임현민2•원혜진2•박혜경2•이반석2•안효승2•주혜원2•김상현2•박원도2 |
| 일곡병원1, 인제대학교 의과대학 상계백병원 내과학교실2 |
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| Abstract |
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Purpose : Contrast media-induced nephropathy (CIN) following coronary angiography is associated with an increased mortality and morbidity. We investigated the incidence of nephrotoxicity, clinical characteristics, laboratory characteristics and risk factors of CIN in patients undergoing coronary angiography.
Methods : We retrospectively evaluated the medical records of 555 patients who had undergone coronary angiography at the Sanggye Paik Hospital, from January 2004 to December 2005. We defined CIN as any increase in the creatinine value of more than 0.5 mg/dL or 50% of baseline value.
Results : Among 555 patients, CIN developed in 10 of 48 patients (20.8%) with renal insufficiency (serum creatinine ≥1.4 mg/dL) and in 7 of 507 patients (1.4%) without renal insufficiency (p<0.001). Decreased renal function, congestive heart failure, higher baseline uric acid, lower baseline albumin and age ≥65 years were the significant predictors of CIN. There were no statistical differences in contrast type and volume according to the development of CIN.
Conclusion : Our data supported the assumption that renal insufficiency, congestive heart failure, hyperuricemia and anemia may be the risk factors of developing CIN. |
| Key Words:
Contrast media, Coronary angiography, Renal insufficiency, Uric acid |
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