Korean Journal of Nephrology 2008;27(1):145-148.
Acute Arsine (AsH3) Intoxication
Sun-Min Kim, M.D., Tae-Young Kim, M.D., Kwang-Sun Lee, M.D., Do-Hyoung Kim, M.D. Kyung-Eun Lee, M.D., Dong-Jin Oh, M.D. and Suk-Hee Yu, M.D.
Department of Internal Medicine, Chung Ang University College of Medicine, Seoul, Korea
증례 : 급성 아르신 가스 중독 1예
김선민·김태영·이광선·김도형·이경은·이정안·오동진·유석희
중앙대학교 의과대학 내과학교실
Abstract
The present report describes a case of arsine intoxication. A 36-year-old male technician who handled gas in a semiconductor laboratory was admitted with severe abdominal pain and dark-red-colored urine. He was exposed to arsine gas while changing a gas bomb, since he mistook an arsine bomb for another, a different kind of a bomb. About 30 minutes after exposure, he suffered colicky abdominal pain, nausea, vomiting and dizziness. He noticed gross hematuria one hour later. On hospital in-patient day 2, the 24 h urine arsenic level was >1,000 μg/day, and the serum arsenic level was 309.4 μg/L. Since BUN/ creatinine level had risen to 33/2.0 mg/dL at this stage, a hemoperfusion was performed. And then hydration was used to maintain urine output at 2 mL/kg/h. His condition had improved, although he complained of a severe headache which was a neuropathic sequela of arsenic exposure. He was discharged with a normal blood arsine level. To our knowledge, this is the second report of arsine poisoning in Korea but somewhat different from the first case.
Key Words: Arsine, Intoxication, Hemolysis, Acute renal failure
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