Korean Journal of Nephrology 2009;28(6):610-616.
Constipation is Closely Associated with Depression in Patients with End-Stage Renal Disease Undergoing Hemodialysis or Peritoneal Dialysis
So Yeon Choi, M.D.1, Min-Ok Kim, M.D.2, Hyun-Ju Choi, M.D.2, SoonKil Kwon, M.D.3, Hyun-Jung Kim, M.D.4, Hyunjeong Baek, M.D.5, Eun Hee Jang, M.D.6, Su-In Yoon, M.D.7 and Hye-young Kim, M.D.3
Department of medicine, Seoul Adventist Hospital1
Eulji University2 Chungbuk National University3
Gyeongsang National University4 Kangwon National University5
Cheju National University6
Earm’s Clinic7
원저 : Constipation is Closely Associated with Depression in Patients with End-Stage Renal Disease Undergoing Hemodialysis or Peritoneal Dialysis
So Yeon Choi, M.D.1, Min-Ok Kim, M.D.2, Hyun-Ju Choi, M.D.2, SoonKil Kwon, M.D.3, Hyun-Jung Kim, M.D.4, Hyunjeong Baek, M.D.5, Eun Hee Jang, M.D.6, Su-In Yoon, M.D.7 and Hye-young Kim, M.D.3
Department of medicine, Seoul Adventist Hospital1, Eulji University2 Chungbuk National University3, Gyeongsang National University4 Kangwon National University5, Cheju National University6, Earm’s Clinic7
Abstract
Purpose:Constipation is a frequent complaint among dialysis patients. However, factors that contribute to constipation in these patients have not been evaluated rigorously. The aim of study was to assess the prevalence and factors that contribute to constipation in patients with End-Stage Renal Disease (ESRD) undergoing hemodialysis (HD) or peritoneal dialysis (PD). Methods:Patients undergoing HD or PD for more than six months in the six dialysis centers were asked to complete a self-administered questionnaire that is designed to assess constipation by Rome- III criteria. Beck depression inventory (BDI) were assessed. A total of 146 patients (HD 91, PD 55) completed the study. Results:The prevalence of constipation was 33% in 91 HD patients and 31% in 55 PD patients. Prevalence of constipation was 32% and did not differ by dialysis mode. Older age, unemployed state, high cumulative illness rating scale and high BDI were associated with constipation. In multivariate analysis, BDI was an independent factor associated with constipation. The prevalence of constipation was 18% and 50% for patients with BDI <15 and ≥15, respectively. The odd ratio for constipation in patients with BDI ≥15 was 3.4 (95% CI, 1.4-8.1). Conclusion:Careful psychogenic attention must be paid to ESRD patients with constipation.
Key Words: Constipation, Depression, End-stage renal disease


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