A Case of Rhabdomyolysis and Acute Renal Failure Associated with Salmonella Enteritidis

Korean Journal of Nephrology 2010;29(4):509-512.

Young Sub Kim, M.D., Jae Won Yang, M.D., So Yeon Park, M.D., Shin Han Song, M.D., Jong Myeong Yu, M.D., Seung Ok Choi, M.D. and Byoung Geun Han, M.D.

Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea

증례 : Salmonella Enteritidis 감염증 환자에게서 발생한 횡문근 융해증 및 급성 신부전 1예

김영섭, 양재원, 박소연, 송신한, 유종명, 최승옥, 한병근

연세대학교 원주의과대학 내과학교실

Abstract

Rhabdomyolysis varies from transient elevation of muscular enzyme to reduction of circulating volume and development of acute kidney injury (AKI). The majority is related to trauma, excessive exercise, alcohol and seizure disorders. Systemic infections associated with salmonellosis were rarely reported. Most of Salmonella infections are caused by Salmonella Typhi. Most common manifestations are typhoid fever and gastroenteritis. Sometimes serious complications such as gastrointestinal bleeding, intestinal perforation, and encephalopathy occur. However, AKI-associated rhabdomyolysis is rarely reported in salmonellosis even though it is not considered to be a major complication. Unfortunately, the precise pathogenetic mechanisms responsible for rhabdomyolysis with Salmonella Enteritidis infection are poorly understood due to the rarity of reported cases. In this presentation, we describe a patient with Salmonella Enteritidis (serogroup D) bacteremia complicated by disseminated intravascular coagulation, rhabdomyolysis and AKI. The blood culture and stool culture from the patient yielded Salmonella Enteritidis. Rhabdomyolysis and AKI should be considered as potentially fatal complications in patients with Salmonella Enteritidis infection.

Key Words: Acute renal failure, Rhabdomyolysis, Salmonella Enteritidis