| A Case of Crescentic Glomerulonephritis Superimposed on Membranous Glomerulopathy |
| A Jin Cho, M.D.1, Jin Hee Lee, M.D.1, Byeongho Jeong, M.D.1, Seungmin Chung, M.D.1, Jung Eun Lee, M.D.1, Gee-Young Kwon, M.D.2, Wooseong Huh, M.D.1, Yoon-Goo Kim, M.D.1, Dae Joong Kim, M.D.1 and Ha Young Oh, M.D.1 |
Departments of Internal Medicine1 and Pathology2
Samsung Medical Center Sungkyunkwan University School of Medicine, Seoul, Korea |
| 증례 : 무증상 원발성 막성 신병증에 병발한 반월상 사구체 신염 1례 |
| 조아진1, 이진희1, 정병호1, 정승민1, 이정은1, 권기영2, 허우성1, 김윤구1, 김대중1, 오하영1 |
| 성균관대학교 의과대학 삼성서울병원 내과1 , 병리과2 |
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| Abstract |
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Membranous glomerulopathy (MGN) is a common cause of nephrotic syndrome in adults. Renal failure gradually develops in patients with MGN and crescentic glomerulonephritis (CGN) superimposed on MGN is a rare cause of acute renal failure. In most cases patients showed nephrotic syndrome with acute renal failure. We report a 33-year-old woman with azotemia but with no other symptoms such as nephrotic syndrome she had been diagnosed to have MGN 15 months before. There seemed to be no other cause of azotemia. Renal biopsy was performed and revealed CGN on existing MGN. She was treated with immunosuppression treatment and azotemia was improved. When unexplained azotemia develops in patients with MGN, we should promptly investigate superimposed conditions including CGN. In CGN superimposed on MN, a potentially reversible condition with appropriate immunosuppression therapy should be considered. |
| Key Words:
Membranous glomerulopathy, Nephrotic syndrome, Immunosuppression |
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