A Case of Invasive Aspergillosis Limited to Renal Allograft

Korean Journal of Nephrology 2010;29(2):300-304.

Owen Kwon, M.D., Jae Gon Woo, M.D., Ji eun Yi, M.D., Gyung Won Jung, M.D., Sung Cho, M.D. and Sung Rok Kim, M.D.

Department of Internal Medicine, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Korea

증례 : 이식신에 국소성으로 발생한 침습성 아스페르길루스증 1예

권오언, 우재곤, 이지은, 정경원, 조 성, 김성록

성균관대학교 의과대학 마산삼성병원 내과

Abstract

Though the development of immunosuppressive agents has increased the survival rate of transplanted kidneys, the opportunistic infection has increased in transplant recipients. Aspergillus may cause invasive aspergillosis via sino-pulmonary route in immunocompromized patients. We report a rare case of invasive aspergillosis of a transplanted kidney without having disseminated disease. A 41 year-old female, who underwent cadaveric renal transplantation 10 months ago, presented with diarrhea and anemia. Ultrasound examination and CT scan revealed an abscess lesion in the transplanted kidney. Surgical curettage and percutaneous drainage were performed. Because, microscopic examination demonstrated fungal hyphae consistent with Aspergillus species, antifungal agents were prescribed. Later, partial transplant nephrectomy and embolization of the remnant kidney were performed.

Key Words: Aspergillus, Invasive aspergillosis, Renal/kidney transplantation