Korean Journal of Nephrology 2010;29(1):115-119.
The Role of Positron-Emission Tomography in Diagnosis and Assessment of Treatment Response in Takayasu Arteritis
Se Woo Park, M.D.1, Chang Hwa Lee, M.D.1, Gheun-Ho Kim, M.D.1 Myung Ho Jeong, M.D.1, Soo Yuck Park, M.D.1, Soon Yeong Song, M.D.2 Yun-Young Choi, M.D.3 and Chong Myung Kang, M.D.1
Departments of Internal Medicine1
Radiology2 and Nuclear Medicine3 Hanyang University College of Medicine
증례 : 타카야수 동맥염의 진단과 치료 과정에서 Positron-Emission Tomography의 역할
박세우1, 이창화1, 김근호1, 정명호1, 박수역1, 송순영2, 최윤영3, 강종명1
한양대학교 의과대학 내과학교실1 , 영상의학교실2 , 핵의학교실3
Abstract
Takayasu arteritis is a nonspecific granulomatous inflammatory arteriopathy of unknown cause that results in occlusive obliteration and less commonly aneurysmal degeneration of large and medium-sized elastic arteries. The diagnosis of Takayasu arteritis and the assessment of its progression and extent remain challenging, especially in patients presenting with a constellation of non-specific symptoms and laboratory tests. The standard diagnostic procedures include biopsy, arteriography, sonography, and magnetic resonance angiography. However, these procedures are invasive or largely operator-dependent, and document only morphological changes such as stenosis, occlusion and aneurysmal transformation which mainly occur in late stages of the disease. On the other hand, Positron-emission tomography is an operator-independent, non-invasive metabolic imaging modality which plays a major role in diagnosis of nonspecific inflammatory diseases. We report a case in which Positron-emission tomography was applied to the detection of Takayasu arteritis and assessment of its disease progression.
Key Words: Takayasu arteritis, Positron-Emission Tomography, Disease progression, Diagnosis
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