| A Case of Clopidogrel-induced Neutropenia in Chronic Renal Failure |
| Gi-Youn Hong, M.D., Han Gyung Seon, M.D., Joon Gu Cheong, M.D., Sae Kyung Joo, M.D. Min Kyoung Kang, M.D., Ji Eun Lee, M.D., Ju Hwan Kim, M.D., Seung Won Koo, M.D. Kyoung Mi Park, M.D., So-Yung Lee, M.D., Dong Ho Yang, M.D. and Hyung-Jong Kim, M.D. |
| Department of Internal Medicine, College of Medicine, CHA University, Seongnam, Korea |
| 증례 : 만성 신부전 환자에서 clopidogrel에 의해 유발된 호중구감소증 1예 |
| 홍기연, 선한경, 정준구, 주세경, 강민경, 이지은, 김주환, 구승원, 박경미, 이소영, 김형종, 양동호 |
| CHA 의과대학교 분당차병원 내과학교실 |
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| Abstract |
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Clopidogrel, a thienopyridine derivative, is an anti-platelet agent that acts as an antagonist of the platelet adenosine diphosphate receptor and considered for essential prophylaxis for intracoronary stent thrombosis in the treatment of ischemic heart disease. Clopidogrel is considered as safe as aspirin but a few cases of severe hematologic adverse reactions associated with clopidogrel had been reported such as neutropenia, aplastic anemia, thrombocytopenic purpura, and thrombocytopenia. We report a rare case of neutropenia induced by clopidogrel in chronic renal failure in a patient who underwent percutaneous coronary intervention. |
| Key Words:
Clopidogrel, Neutropenia, Chronic renal failure |
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