Korean Journal of Nephrology 2011;30(6):622-628.
Hydration Status in Elderly Hemodialysis Patients: Bioimpedance Analysis
Shina Lee, M.D, Hye Rim An, M.D., Jung-Hwa Ryu, M.D., Mina Yu, M.D., Dong-Ryeol Ryu, M.D., Seung-Jung Kim, M.D., Duk-Hee Kang, M.D. and Kyu Bok Choi, M.D.
Department of Internal Medicine, School of Medicine, Ewha Womans University, Seoul, Korea
원저 : 고령 혈액투석 환자에서 바이오임피던스법으로 측정한 체수분량 상태
이신아, 안혜림, 류정화, 유민아, 류동열, 김승정, 강덕희, 최규복
이화여자대학교 의학전문대학원 내과학교실
Abstract
Purpose: This study was aimed to compare hydration status between young and elderly end-stage renal disease (ESRD) patients on hemodialysis (HD) and to analyze factors related to overhydration. Methods: We measured fluid status before a mid-week HD session in clinically stable 47 patients on maintenance HD using bioimpedance spectroscopy (BIS) device. In addition, weight and blood pressure (BP) were recorded during the treatment. Results: Participants were divided into young (<65 years, n=32) and elderly (≥65 years, n=15) patients. In elderly patients, pre-HD diastolic BP, intracellular water (ICW), and lean tissue index (LTI) were significantly lower and extracellular water (ECW)/total body water (TBW) was significantly higher than in young patients. However, there were no differences in pre-HD body mass index (BMI), ultrafiltration volume, pre-HD systolic BP, TBW, ECW, and fat tissue index between the two groups. ECW/TBW ratio and LTI were significantly correlated with age. In a multivariate regression analysis, age and pre-HD pulse pressure were significantly associated with ECW/TBW. Conclusion: Although BMI and TBW of elderly ESRD patients were similar to those of young patients, ICW and LTI were lower and ECW/TBW was higher in elderly patients than in young patients. Therefore, clinical manifestations related to overhydration may develop more frequently in elderly patients compared with young patients.
Key Words: Body composition, Edema, Renal dialysis, Aged


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