Korean Journal of Nephrology 2011;30(4):394-398.
Rhabdomyolysis-Induced Acute Kidney Injury Associated with Posterior Reversible Encephalopathy Syndrome
Woo Jeung Kim, M.D., Seong Kyo Park, M.D., Hoon Young Choi, M.D., Sung Kyu Ha, M.D. and Hyeong Cheon Park, M.D.
Department of Internal Medicine, Yonsei University, Gangnam Severance Hospital, College of Medicine, Seoul, Korea
증례 : 횡문근융해증에 의한 급성 신손상 환자에서 발생한 고혈압성가역적후두부뇌병증 증후군 1예
김우정, 박승교, 최훈영, 하성규, 박형천
연세대학교 의과대학 내과학교실, 강남세브란스병원 신장내과
Posterior reversible encephalopathy syndrome (PRES) is characterized by altered mental status, headache, vomiting, visual loss, seizure and reversible posterior subcortical white matter and cortex edema in brain image studies. It is often associated with malignant hypertension and immunosuppression. We present a 30-year-old male with PRES. He was admitted to our hospital with rhabdomyolysis and acute kidney injury (AKI). During the hospital course, he developed acute malignant hypertension accompanied by visual loss and generalized seizure. Brain MRI demonstrated increased signal intensity with gyral swelling in cerebellar hemisphere, parieto-occipital cortex, and subcortical white matter area. Following aggressive blood pressure control and hemodialysis the patient recovered fully without any neurologic or visual complications. We report a case of PRES associated with AKI due to rhabdomyolysis.
Key Words: Posterior reversible encephalopathy syndrome, Acute kidney injury, Rhabdomyolysis

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