Korean Journal of Nephrology 2011;30(4):399-403.
A Case of Minimal Change Nephrotic Syndrome Presented as Portal Vein Thrombosis and Acute Renal Failure
Hee Sun Kwon, M.D.1, Ah Young Shin, M.D.1, Hwa Young Lee, M.D.1, Sung Yeon Cho, M.D.1, Min Ju Kim, M.D.1, Yu Seon Yun, M.D.1, Hyun Gyung Kim, M.D.1, Young Soo Kim, M.D.1, Yeong Jin Choi, M.D.2 and Young Ok Kim, M.D.1
Department of Internal Medicine1
College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Pathology2
College of Medicine, The Catholic University of Korea, Seoul, Korea
증례 : 급성신부전증과 간문맥 혈전증으로 발현한 미세변화신증후군 1예
권희선1, 신아영1, 이화영1, 조성연1, 김민주1, 윤유선1, 김현경1, 김영수1, 최영진2, 김영옥1
가톨릭대학교 의과대학 내과학교실1 , 병리과학교실2
Patients with the nephrotic syndrome are at risk of developing thromboembolic complications. Much evidence suggests that a hypercoagulable state exists in the setting of the nephrotic syndrome, but the exact mechanisms are poorly understood. The nephrotic syndrome associated with portal vein thrombosis is relatively uncommon. We experienced a case of minimal change nephrotic syndrome presented as portal vein thrombosis and acute renal failure. On renal biopsy, electron microscopic examination reveals diffuse foot process effacement. Treatment with corticosteroid and anticoagulation resulted in complete remission of proteinuria.
Key Words: Minimal change nephrotic syndrome, Portal vein, Thrombosis, Acute kidney injury

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