Reliability of Hemodialysis Adequacy Measured by Ionic Dialysance |
Joon Seok Oh, M.D.1, Sung Min Kim, M.D.1, Yong Hun Sin, M.D.1, Joong Kyung Kim, M.D.1, Young Ki Son, M.D.2, Won Suk An, M.D.2, Seong Eun Kim, M.D.2 and Ki Hyun Kim, M.D.2 |
Department of Internal Medicine1 Bong Seng Hospital, Department of Internal Medicine2 Dong-a University College of Medicine |
원저 : 이온치환투석제거율로 측정한 적절 혈액투석의 신뢰도 |
오준석1, 김성민1, 신용훈1, 김중경1, 손영기2, 안원석2, 김성은2, 김기현2 |
봉생병원 내과1 , 동아대학교 의과대학 내과학교실2 |
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Abstract |
Purpose: Quantification of the dialysis dose is an essential element in the management of hemodialysis. The author investigates the reliability of hemodialysis adequacy measured by ionic dialysance (Online clearance monitoringⓇ, OCM). Because OCM is a non-invasive and instantly accessible method, it could be replaced Kt/V derived from single-pool variable volume urea kinetic model (UKM).
Methods: Kt/V using UKM and OCM were measured simultaneously in 51 patients who have received hemodialysis therapy via arteriovenous fistula. The analysis of the data collected from 186 hemodialysis sessions were performed.
Results: Kt/V of conventional hemodialysis, high efficiency hemodialysis and hemodiafiltration measured by UKM were 1.39±0.24, 1.41±0.23 and 1.53±0.17, and by OCM were 1.24±0.17, 1.26±0.19 and 1.39±0.19, respectively. The data of UKM were significantly higher than those of OCM (p=0.00). Also, there were strong positive correlations between UKM and OCM in hemodialysis (r=0.80, p=0.00), high efficiency hemodialysis (r=0.65, p=0.00) and hemodiafiltration (r=0.67, p=0.00).
Conclusion: The Kt/V using OCM measured by ionic dialysance provided slightly lower data than that of UKM derived from single-pool variable volume urea kinetic model, but it may be a reliable test to evaluate dialysis adequacy in conventional hemodialysis, high efficiency hemodialysis and hemodiafiltration. |
Key Words:
Hemodialysis, Efficiency, Urea |
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