Korean Journal of Nephrology 1983;2(2):83-92.

만성 신부전증 환자의 좌심실가능

김병광 , 우무영 , 정시전 , 이희발

Abstract

Left ventricular function was evaluated by M-mode echocardiography in 22 normal subjects (normal con- trol), 15 patients with chronic renal failure who have not yet received dialysis therapy(uremic control), 17 patients who have performed CAPD for at least 3 months (CAPD group) and 11 patients who have been on maintenance hemodialysis for more than 3 months. Of 11 hemodialysis patients, 7 patients were studied immediately before hemodialysis(prehemodi- alysis group) and 9 patients immediately after hemodi- .alysis(posthemodialysis group). 5 patients were studied before and after hemodialysis. Left ventricular systolic internal dimension(LVIDs) .and left ventricular diastolic internal dimension(LVIDd) were significantly greater in 4 groups with chronic renal failure as compared to normal control. LVIDs was, however, significantly smaller in CAPD group and posthemodialysis group when compared to uremic control. There were no difference in LVIDd among 4 groups with chronic renal failure. Ejection time was not different among 5 groups. Ejection fraction (EF), mean velosity of circumferential fiber shortening (Mvcf) and % Fractional shortening(% FS) were significantly decreased in uremic control but not in CAPD and two hemodialysis groups. Cardiac output was significantly greater in two hemodialysis groups when compared to normal control. In conclusion, left ventricular function was significantly decreased in uremic control but improved to normal control level after CAPD or hemodialysis. No difference in left ventricular function was observed when studied immediately before and after hemodialy sis. The improvement in left ventricular function after CAPD and hemodialysis was related in part to a decrease in LVIDs after CAPD or hemodialysis.