Editorial

July 5, 2024


Brief review for “Machine learning-based 2-year risk prediction tool in immunoglobulin A nephropathy
Hae-Ryong Yun, Tae-Hyun Yoo
Kidney Res Clin Pract. 2024;43(6):697-699.

Editorial

August 12, 2024


What is the final destination of hemodialysis membrane?
Jae Won Yang
Kidney Res Clin Pract. 2024;43(6):700-702.

Special Article

August 7, 2024


Pathological and functional significance of aging mouse kidneys: clinical implications to reduce the risk of hyper- or hypokalemia in the elderly
Itsuro Kazama
Kidney Res Clin Pract. 2024;43(6):703-708.

Review Article

February 6, 2024


Precision medicine for focal segmental glomerulosclerosis
Yi Xie, Fei Liu
Kidney Res Clin Pract. 2024;43(6):709-723.

Review Article

November 18, 2024


The crosstalk of Wnt/β-catenin signaling and p53 in acute kidney injury and chronic kidney disease
Wen-Hua Ming, Lin Wen, Wen-Juan Hu, et al.
Kidney Res Clin Pract. 2024;43(6):724-738.

Original Article

October 27, 2023


Machine learning-based 2-year risk prediction tool in immunoglobulin A nephropathy
Yujeong Kim, Jong Hyun Jhee, Chan Min Park, et al.
Kidney Res Clin Pract. 2024;43(6):739-752.

Original Article

January 25, 2024


Medium cut-off dialyzer improves reduction ratios of large middle molecules associated with vascular calcification
Hyo Jin Kim, Eun Young Seong, Sang Heon Song
Kidney Res Clin Pract. 2024;43(6):753-762.

Original Article

August 10, 2023


Pan-Nox inhibitor treatment improves renal function in aging murine diabetic kidneys
Jeong Hoon Park, Sung Gi Yoon, Jung Yeon Ghee, et al.
Kidney Res Clin Pract. 2024;43(6):763-773.

Original Article

August 10, 2023


Indoxyl sulfate induces apoptotic cell death by inhibiting glycolysis in human astrocytes
Seung-Hyun Jeong, Samel Park, Jae-sung Choi, et al.
Kidney Res Clin Pract. 2024;43(6):774-784.

Original Article

May 29, 2024


The association between transferrin saturation and all-cause mortality in chronic kidney disease: findings from Korean Cohort Study for Outcome in Patients with Chronic Kidney Disease
Eunmi Jo, Hyo Jin Kim, Jayoun Kim, et al.
Kidney Res Clin Pract. 2024;43(6):785-796.

Original Article

November 28, 2024


Circulating microRNAs as markers for scrub typhus-associated acute kidney injury
Haeun Lee, Jung Min Kim, A Young Cho, et al.
Kidney Res Clin Pract. 2024;43(6):797-806.

Original Article

August 10, 2023


Intrinsic prefrontal functional connectivity according to cognitive impairment in patients with end-stage renal disease
Kang Min Park, Chang Min Heo, Dong Ah Lee, et al.
Kidney Res Clin Pract. 2024;43(6):807-817.

Original Article

August 30, 2023


The impact of severe depression on the survival of older patients with end-stage kidney disease
You Hyun Jeon, Jeong-Hoon Lim, Yena Jeon, et al.
Kidney Res Clin Pract. 2024;43(6):818-828.

Images in Practice

November 18, 2024


Unilateral polycystic kidney with PKHD1 gene mutation
Joung-Hyun Park, Hye-Won Woo, Bum-Sang Cho, et al.
Kidney Res Clin Pract. 2024;43(6):829-831.

Correspondence

November 28, 2024


Fostering international coordination in renal disaster preparedness: a collaboration between the Renal Disaster Preparedness Working Group of the International Society of Nephrology and the Disaster Preparedness and Response Committee of the Korean Society of Nephrology
Kyung Don Yoo, Sunhwa Lee, Hayne Cho Park, et al.
Kidney Res Clin Pract. 2024;43(6):832-835.
Editorials
Brief review for “Machine learning-based 2-year risk prediction tool in immunoglobulin A nephropathy
Hae-Ryong Yun, Tae-Hyun Yoo
Kidney Res Clin Pract. 2024;43(6):697-699.   Published online July 5, 2024
What is the final destination of hemodialysis membrane?
Jae Won Yang
Kidney Res Clin Pract. 2024;43(6):700-702.   Published online August 12, 2024
Special Article
Pathological and functional significance of aging mouse kidneys: clinical implications to reduce the risk of hyper- or hypokalemia in the elderly
Itsuro Kazama
Kidney Res Clin Pract. 2024;43(6):703-708.   Published online August 7, 2024
Elderly patients are prone to develop hyper- or hypokalemia, since they are susceptible to drugs or diets that affect the urinary or fecal potassium (K+) excretion. In aging mouse kidneys, in addition to glomerulosclerosis, proximal tubular atrophy, and atherosclerosis in renal arterioles, there was diffuse tubulointerstitial fibrosis with a number of inflammatory leukocytes infiltrating into the cortical interstitium. Since these...
Review Articles
Precision medicine for focal segmental glomerulosclerosis
Yi Xie, Fei Liu
Kidney Res Clin Pract. 2024;43(6):709-723.   Published online February 6, 2024
Focal segmental glomerulosclerosis (FSGS) is one of the common causes of nephrotic syndrome in adults and children worldwide. FSGS consists of a group of kidney diseases classified based on specific histopathological features. The current classification of FSGS makes it difficult to distinguish individual differences in pathogenesis, disease progression, and response to treatment. In recent years, the spread of next-generation sequencing,...
The crosstalk of Wnt/β-catenin signaling and p53 in acute kidney injury and chronic kidney disease
Wen-Hua Ming, Lin Wen, Wen-Juan Hu, Rong-Fang Qiao, Yang Zhou, Bo-Wei Su, Ya-Nan Bao, Ping Gao, Zhi-Lin Luan
Kidney Res Clin Pract. 2024;43(6):724-738.   Published online November 18, 2024
Wnt/β-catenin is a signaling pathway associated with embryonic development, organ formation, cancer, and fibrosis. Its activation can repair kidney damage during acute kidney injury (AKI) and accelerate the occurrence of renal fibrosis after chronic kidney disease (CKD). Interestingly, p53 has also been found as a key modulator in AKI and CKD in recent years. Meantime, some studies have found crosstalk...
Original Articles
Machine learning-based 2-year risk prediction tool in immunoglobulin A nephropathy
Yujeong Kim, Jong Hyun Jhee, Chan Min Park, Donghwan Oh, Beom Jin Lim, Hoon Young Choi, Dukyong Yoon, Hyeong Cheon Park
Kidney Res Clin Pract. 2024;43(6):739-752.   Published online October 27, 2023
Background: This study aimed to develop a machine learning-based 2-year risk prediction model for early identification of patients with rapid progressive immunoglobulin A nephropathy (IgAN). We also assessed the model’s performance to predict the long-term kidney-related outcome of patients. Methods: A retrospective cohort of 1,301 patients with biopsy-proven IgAN from two tertiary hospitals was used to derive and externally validate...
Medium cut-off dialyzer improves reduction ratios of large middle molecules associated with vascular calcification
Hyo Jin Kim, Eun Young Seong, Sang Heon Song
Kidney Res Clin Pract. 2024;43(6):753-762.   Published online January 25, 2024
Background: We aimed to investigate the change in the large middle molecule (>15 kDa) removal rate, which is associated with vascular calcification, when using a medium cut-off (MCO) dialyzer compared to a high-flux (HF) dialyzer. Methods: Twenty patients with clinically stable maintenance hemodialysis were investigated over a 15-week study period. Dialyzer efficacies were evaluated during the last midweek hemodialysis treatment...
Pan-Nox inhibitor treatment improves renal function in aging murine diabetic kidneys
Jeong Hoon Park, Sung Gi Yoon, Jung Yeon Ghee, Ji Ae Yoo, Jin Joo Cha, Young Sun Kang, Sang Youb Han, Yun Jae Seol, Jee Young Han, Dae Ryong Cha
Kidney Res Clin Pract. 2024;43(6):763-773.   Published online August 10, 2023
Background: Aging is a risk factor for development of chronic kidney disease and diabetes mellitus with commonly shared features of chronic inflammation and increased oxidative stress. Here, we investigated the effect of pan-Nox-inhibitor, APX-115, on renal function in aging diabetic mice. Methods: Diabetes was induced by intraperitoneal injection of streptozotocin at 50 mg/kg/day for 5 days in 52-week-old C57BL/6J mice....
Indoxyl sulfate induces apoptotic cell death by inhibiting glycolysis in human astrocytes
Seung-Hyun Jeong, Samel Park, Jae-sung Choi, Nam-Jun Cho, Jong-Seok Moon, Hyo-Wook Gil
Kidney Res Clin Pract. 2024;43(6):774-784.   Published online August 10, 2023
Background: Neurologic complications, such as cognitive and emotional dysfunction, have frequently been observed in chronic kidney disease (CKD) patients. Previous research shows that uremic toxins play a role in the pathogenesis of CKD-associated cognitive impairment. Since astrocytes contribute to the protection and survival of neurons, astrocyte function and brain metabolism may contribute to the pathogenesis of neurodegeneration. Indoxyl sulfate (IS)...
The association between transferrin saturation and all-cause mortality in chronic kidney disease: findings from Korean Cohort Study for Outcome in Patients with Chronic Kidney Disease
Eunmi Jo, Hyo Jin Kim, Jayoun Kim, Tae-Hyun Yoo, Yaeni Kim, Soo Wan Kim, Kook-Hwan Oh, Eun Young Seong, Sang Heon Song
Kidney Res Clin Pract. 2024;43(6):785-796.   Published online May 29, 2024
Background: Transferrin saturation (TSAT) has been used as an indicator of iron deficiency. However, there is no consensus regarding its optimal range for patient with chronic kidney disease (CKD). We aimed to analyze the effect of TSAT on the prognosis of patients with non-dialysis CKD (NDCKD). Methods: From 2011 to 2016, 2157 NDCKD patients with baseline TSAT measurements were followed...
Circulating microRNAs as markers for scrub typhus-associated acute kidney injury
Haeun Lee, Jung Min Kim, A Young Cho, Ju Hwan Oh, Kwang Young Lee, Chang-Seop Lee, In O Sun
Kidney Res Clin Pract. 2024;43(6):797-806.   Published online November 28, 2024
Background: Circulating microRNAs (miRNAs) are potential biomarkers for various kidney diseases. In this study, we aimed to identify a circulating miRNA signature for detecting acute kidney injury (AKI) in scrub typhus. Methods: We prospectively enrolled 40 patients with scrub typhus (20 with AKI, AKI group; 20 without AKI, non-AKI group) and 20 healthy volunteers (the HV group). Thereafter, we performed...
Intrinsic prefrontal functional connectivity according to cognitive impairment in patients with end-stage renal disease
Kang Min Park, Chang Min Heo, Dong Ah Lee, Hyuk Huh, Sihyung Park, Yang Wook Kim, Yoo Jin Lee, Hyeok Jin Yoon, Bong Soo Park
Kidney Res Clin Pract. 2024;43(6):807-817.   Published online August 10, 2023
Background: This study aimed to investigate differences in intrinsic prefrontal functional connectivity according to the presence of cognitive impairment in patients with end-stage renal disease (ESRD) using functional near-infrared spectroscopy (fNIRS). Methods: We prospectively enrolled 37 patients with ESRD who had been undergoing hemodialysis for more than 6 months and had no history of neurological or psychiatric disorders. All patients...
The impact of severe depression on the survival of older patients with end-stage kidney disease
You Hyun Jeon, Jeong-Hoon Lim, Yena Jeon, Yu-Kyung Chung, Yon Su Kim, Shin-Wook Kang, Chul Woo Yang, Nam-Ho Kim, Hee-Yeon Jung, Ji-Young Choi, Sun-Hee Park, Chan-Duck Kim, Yong-Lim Kim, Jang-Hee Cho
Kidney Res Clin Pract. 2024;43(6):818-828.   Published online August 30, 2023
Background: Incidence of depression increases in patients with end-stage kidney disease (ESKD). We evaluated the association between depression and mortality among older patients with ESKD, which has not been studied previously. Methods: This nationwide prospective cohort study included 487 patients with ESKD aged >65 years, who were categorized into minimal, mild-to-moderate, and severe depression groups based on their Beck Depression...
Images in Practice
Unilateral polycystic kidney with PKHD1 gene mutation
Joung-Hyun Park, Hye-Won Woo, Bum-Sang Cho, Hye-Young Kim
Kidney Res Clin Pract. 2024;43(6):829-831.   Published online November 18, 2024
Correspondence
Fostering international coordination in renal disaster preparedness: a collaboration between the Renal Disaster Preparedness Working Group of the International Society of Nephrology and the Disaster Preparedness and Response Committee of the Korean Society of Nephrology
Kyung Don Yoo, Sunhwa Lee, Hayne Cho Park, Won Min Hwang, Jung Pyo Lee, Adrian Liew, Ali Abu-Alfa, Hyeong Cheon Park, Young-Ki Lee
Kidney Res Clin Pract. 2024;43(6):832-835.   Published online November 28, 2024

Kidney Research
and
Clinical Practice

Print ISSN: 2211-9132
Online ISSN: 2211-9140


ABOUT
BROWSE ARTICLES
EDITORIAL POLICY
FOR CONTRIBUTORS
Editorial Office
#301, (Miseung Bldg.) 23, Apgujenog-ro 30-gil, Gangnam-gu, Seoul 06022, Korea
Tel: +82-2-3486-8736    Fax: +82-2-3486-8737    E-mail: registry@ksn.or.kr                

Copyright © 2024 by The Korean Society of Nephrology.

Developed in M2PI

Close layer