Kidney Research and Clinical Practice

Editorial

A troubled mind troubles the kidney: a brain-to-kidney axis?

Keun You Kim, Eosu Kim

Kidney Res Clin Pract. 2022;41(6):637-639. Published online November 30, 2022

DOI: https://doi.org/10.23876/j.krcp.22.234

The effects of nitric oxide and 8-iso-prostaglandin F2α on chloride absorption in cortical thick ascending limb

Tae-Hwan Kwon

Kidney Res Clin Pract. 2022;41(6):640-643. Published online November 28, 2022

DOI: https://doi.org/10.23876/j.krcp.22.179

Review Article

Healthy aging and chronic kidney disease

Reshma Aziz Merchant, Anantharaman Vathsala

Kidney Res Clin Pract. 2022;41(6):644-656. Published online October 25, 2022

The world population is aging and the prevalence of noncommunicable diseases such as diabetes, hypertension, and chronic kidney disease (CKD) will increase significantly. With advances in medical treatment and public health, the human lifespan continues to outpace the health span in such a way that the last decade of life is generally spent in poor health. In 2015, the World...

DOI: https://doi.org/10.23876/j.krcp.22.112

Nutrition and quality of life in chronic kidney disease patients: a practical approach for salt restriction

Kunitoshi Iseki

Kidney Res Clin Pract. 2022;41(6):657-669. Published online January 21, 2022

Cited By 1

The clinical practice guidelines (CPGs) for nutrition in chronic kidney disease (CKD) were updated after 20 years from the previous guidelines by the Kidney Disease Outcomes Quality Initiative (KDOQI). During this period, the severity of CKD was defined by estimated glomerular filtration rate and albuminuria by the organization Kidney Disease: Improving Global Outcomes. Main risk factors for CKD such as...

DOI: https://doi.org/10.23876/j.krcp.21.203

Why should we focus on high-volume hemodiafiltration?

Sug-Kyun Shin, Young-Il Jo

Kidney Res Clin Pract. 2022;41(6):670-681. Published online February 22, 2022

Though noticeable technological advances related to hemodialysis (HD) have been made, unfortunately, the survival rate of dialysis patients has yet to improve significantly. However, recent research findings reveal that online hemodiafiltration (HDF) significantly improves patient survival in comparison to conventional HD. Accordingly, the number of patients receiving online HDF is increasing. Although the mechanism driving the benefit has not yet...

DOI: https://doi.org/10.23876/j.krcp.21.268

Advances in the management of diabetic kidney disease: beyond sodium-glucose co-transporter 2 inhibitors

Anthony T. P. Chan, Sydney C. W. Tang

Kidney Res Clin Pract. 2022;41(6):682-698. Published online July 19, 2022

Cited By 1

Progress in the treatment of diabetic kidney disease (DKD) has been modest since the early trials on renin-angiotensin-aldosterone system inhibitors (RAASis). Although sodium-glucose co-transporter 2 inhibitors (SGLT2is) have revolutionized the management of DKD by lowering proteinuria and protecting organs, other novel treatment approaches with good evidence and efficacy that can be used in conjunction with a RAASi or SGLT2i in...

DOI: https://doi.org/10.23876/j.krcp.21.285

Original Article

Nitric oxide-inhibited chloride transport in cortical thick ascending limbs is reversed by 8-iso-prostaglandin-F2α

Pablo D. Cabral, Guillermo B. Silva, Sandra T. Baigorria, Luis I. Juncos, Ebenezer I. O. Ajayi, Néstor H. García

Kidney Res Clin Pract. 2022;41(6):699-706. Published online August 17, 2022

Background: Sodium chloride (NaCl) reabsorption in the cortical thick ascending limb (cTAL) is regulated by opposing effects. Nitric oxide (NO) inhibits NaCl reabsorption while 8-iso-prostaglandin-F2α (8-iso-PGF2α) stimulates it. Their interaction has not been evaluated in the cTAL. Because 8-iso-PGF2α has considerable stability while NO is a free radical with a short half-life, we hypothesized that, in the cTAL, the inhibition...

DOI: https://doi.org/10.23876/j.krcp.21.243

Clinical relevance of postoperative proteinuria for prediction of early renal outcomes after kidney transplantation

Junseok Jun, Kyungho Park, Hyun Suk Lee, Kyo Won Lee, Jung Eun Lee, Jae Berm Park, Kyunga Kim, Wooseong Huh, Yoon-Goo Kim, Dae Joong Kim, Hye Ryoun Jang

Kidney Res Clin Pract. 2022;41(6):707-716. Published online July 19, 2022

Background: Proteinuria is associated with poor allograft and patient survival in kidney transplant recipients. However, the clinical relevance of spot urine protein-to-creatinine ratio (PCR) or albumin-to-creatinine ratio (ACR) as predictors of renal outcomes during the early postoperative period following kidney transplantation (KT) has not been determined. Methods: This single-center retrospective cohort study included 353 kidney transplant recipients who underwent KT...

DOI: https://doi.org/10.23876/j.krcp.21.246

Hospital mortality and prognostic factors in critically ill patients with acute kidney injury and cancer undergoing continuous renal replacement therapy

Da Woon Kim, Geum Suk Jang, Kyoung Suk Jung, Hyuk Jae Jung, Hyo Jin Kim, Harin Rhee, Eun Young Seong, Sang Heon Song

Kidney Res Clin Pract. 2022;41(6):717-729. Published online July 19, 2022

Cited By 1

Background: Whether continuous renal replacement therapy (CRRT) should be applied to critically ill patients with both acute kidney injury (AKI) and cancer remains controversial because of poor expected outcomes. The present study determined prognostic factors for all-cause in-hospital mortality in patients with AKI and cancer undergoing CRRT. Methods: We included 471 patients with AKI and cancer who underwent CRRT at the...

DOI: https://doi.org/10.23876/j.krcp.21.305

Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression

Hyunsuk Kim, Jinmo Sung, Ju Young Bae, Poongyeon Lee, Yun Kyu Oh, Hyunho Kim

Kidney Res Clin Pract. 2022;41(6):730-740. Published online June 20, 2022

Background: Autosomal dominant polycystic kidney disease (ADPKD), one of the most common human monogenic diseases, is characterized by the presence of numerous fluid-filled renal cysts and is a leading cause of end-stage renal disease (ESRD). Urinary biomarkers may be useful for predicting the variable course of ADPKD progression from cyst growth to ESRD. Methods: To identify candidate urinary biomarkers of ADPKD...

DOI: https://doi.org/10.23876/j.krcp.21.303

Association of sarcopenia and its components with clinical outcomes in patients undergoing peritoneal dialysis

Seok Hui Kang, A Young Kim, Jun Young Do

Kidney Res Clin Pract. 2022;41(6):741-752. Published online July 19, 2022

Background: Further studies are needed to identify whether muscle mass, muscle strength, or sarcopenia is the best indicator of survival in patients undergoing peritoneal dialysis (PD). We aimed to compare the association of sarcopenia and its components with survival in patients undergoing PD. Methods: We identified all patients with prevalent PD (n = 199). We routinely recommended handgrip strength (HGS) and...

DOI: https://doi.org/10.23876/j.krcp.21.278

Associations among Alzheimer disease, depressive disorder, and risk of end-stage kidney disease in elderly people

Shin Chan Kang, Hee Byung Koh, Hyung Woo Kim, Young Su Joo, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang, Jung Tak Park

Kidney Res Clin Pract. 2022;41(6):753-763. Published online September 8, 2022

Cited By 1

Background: Alzheimer disease (AD) and depressive disorder (DD) are prevalent among elderly end-stage kidney disease (ESKD) patients. However, whether preexisting mental health disorders increase the risk of ESKD is not well understood. The risk of incident ESKD in patients with or without underlying AD or DD was evaluated in a nationwide cohort of elderly people in Republic of Korea. Methods: This...

DOI: https://doi.org/10.23876/j.krcp.21.311

Correspondence

Successful provision of hemodialysis to patients with confirmed COVID-19 in Korea: the role of a cooperative network between public and private medical systems

Ji-Young Choi, Jeong-Hoon Lim, Seungyeup Han, Seung-Chan Park, Hee-Yeon Jung, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim, Sun-Hee Park

Kidney Res Clin Pract. 2022;41(6):764-767. Published online November 16, 2022

DOI: https://doi.org/10.23876/j.krcp.22.102

Treatment of acute tacrolimus toxicity with phenytoin after Paxlovid (nirmatrelvir/ritonavir) administration in a kidney transplant recipient

Eun-Jeong Kwon, Gi-Ae Yun, Seokwoo Park, Sejoong Kim, Dong-Wan Chae, Hyung Sub Park, Taeseung Lee, Jong Cheol Jeong

Kidney Res Clin Pract. 2022;41(6):768-770. Published online November 29, 2022

DOI: https://doi.org/10.23876/j.krcp.22.218

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