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Editorial
March 19, 2025
- Identifying the optimal blood pressure target among Korean hemodialysis patients: current evidence and future directions
- Young Su Joo, Tae-Hyun Yoo
- Kidney Res Clin Pract. 2025;44(2):213-216.
- Editorial
- Identifying the optimal blood pressure target among Korean hemodialysis patients: current evidence and future directions
- Young Su Joo, Tae-Hyun Yoo
- Kidney Res Clin Pract. 2025;44(2):213-216. Published online March 19, 2025
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- Special Articles
- The impact of body mass index on mortality according to age in hemodialysis patients: an analysis of the Korean Renal Data System
- Hyunglae Kim, Seon A Jeong, Yoonjung Cho, Kyeong Min Kim, Sun Deuk Hwang, Sun Ryoung Choi, Hajeong Lee, Ji Hyun Kim, Su Hyun Kim, Tae Hee Kim, Ho-Seok Koo, Chang-Yun Yoon, Kiwon Kim, Seon Ho Ahn, Hye Eun Yoon, Tae Hyun Ban, Yu Ah Hong, Yong Kyun Kim
- Kidney Res Clin Pract. 2025;44(2):217-227. Published online January 16, 2025
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The impact of age on the relationship between body mass index (BMI) and all-cause mortality in hemodialysis (HD) patients is not clearly understood. Using data from the Korean Renal Data System (2001–2022), we analyzed 66,129 HD patients, stratified into young (<65 years, n = 24,589), younger-old (65–74 years, n = 17,732), and older-old (≥75 years, n = 23,808) groups. Patients...
- Disaster emergency meal plans for Korean patients who require hemodialysis
- Yumi Jang, Seong Geun Kim, Sua Lee, Hyun Ho Oh, Nara Shin, Young-Ki Lee, Kyung Don Yoo
- Kidney Res Clin Pract. 2025;44(2):228-237. Published online January 24, 2025
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Proactive planning and preparation are critical to the safety of patients on dialysis during emergencies, such as natural disasters, and pandemics, such as coronavirus disease 2019. Patients with end-stage kidney disease are particularly vulnerable to disruptions such as power outages, water shortages, transportation issues, and dialysis center closures because they can result in missed dialysis sessions and severe health deterioration....
- Review Article
- The pathophysiological significance between autosomal dominant polycystic kidney disease and neutrophil gelatinase-associated lipocalin
- Pallavi Devapatla, Wen-Yih Jeng, Wen-Tai Chiu, Hsiu Mei Hsieh-Li
- Kidney Res Clin Pract. 2025;44(2):238-248. Published online March 12, 2025
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Autosomal dominant polycystic kidney disease (ADPKD) is the most common form of polycystic kidney disease (PKD) and is a typical adult-onset multisystem disorder. It is a progressive disease characterized by the disruption of renal tubular integrity, involving the modulation of cellular proliferation and apoptosis. Most ADPKD results from a mutation in either the PKD1 or PKD2 gene encoding polycystin-1 and...
- Original Articles
- Examine the optimal multidisciplinary care teams for patients with chronic kidney disease from a nationwide cohort study
- Masanori Abe, Tsuguru Hatta, Yoshihiko Imamura, Tsutomu Sakurada, Shinya Kaname
- Kidney Res Clin Pract. 2025;44(2):249-264. Published online October 5, 2023
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Background: Multidisciplinary team-based integrated care (MDC) has been recommended for patients with chronic kidney disease (CKD). However, team-based specific structured care systems are not yet established. Therefore, we investigated the efficacy of MDC system and the optimal number of professionals that make up the team for maintaining kidney function and improving prognosis. Methods: This nationwide, multicenter, observational study included 2,957...
- Associations of metabolic variabilities and cardiovascular outcomes according to estimated glomerular filtration rate in chronic kidney disease: a nationwide observational cohort study
- Jeong Min Cho, Kyungdo Han, Kwon Wook Joo, Soojin Lee, Yaerim Kim, Semin Cho, Hyuk Huh, Seong Geun Kim, Minsang Kim, Eunjeong Kang, Dong Ki Kim, Sehoon Park
- Kidney Res Clin Pract. 2025;44(2):265-276. Published online January 12, 2024
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Background: The impact of baseline estimated glomerular filtration rate (eGFR) on the risk of adverse outcomes according to metabolic parameter variabilities in chronic kidney disease has rarely been investigated. Methods: We conducted a retrospective nationwide cohort study using the National Health Insurance System data in Korea from 2007 to 2013 to identify individuals with three or more health screenings. The...
- Association between dementia diagnosis at dialysis initiation and mortality in older patients with end-stage kidney disease in South Korea
- Byung Min Ye, Seongmin Kang, Woo Yeong Park, Jang-Hee Cho, Byung Chul Yu, Miyeun Han, Sang Heon Song, Gang-Jee Ko, Jae Won Yang, Sungjin Chung, Yu Ah Hong, Young Youl Hyun, Eunjin Bae, In O Sun, Hyunsuk Kim, Won Min Hwang, Sung Joon Shin, Soon Hyo Kwon, Seo Rin Kim, Kyung Don Yoo
- Kidney Res Clin Pract. 2025;44(2):277-287. Published online February 7, 2024
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Background: The prevalence of dementia is 2- to 7-fold higher among patients with end-stage kidney disease (ESKD) than among the general population; however, its clinical implications in this population remain unclear. Therefore, this study aimed to determine whether comorbid dementia increases mortality among older patients with ESKD undergoing newly initiated hemodialysis. Methods: We analyzed data from the Korean Society of...
- Efficacy of intradialytic neuromuscular electrical stimulation and oral nutritional supplementation in hemodialysis patients: a multicenter, randomized controlled trial
- Jae Hyeon Park, Jae Yoon Park, Geum Sil Lee, Ran-hui Cha
- Kidney Res Clin Pract. 2025;44(2):288-298. Published online February 7, 2024
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Background: Sarcopenia is common in hemodialysis patients. This study aimed to evaluate the effect of simultaneous nutritional support and intradialytic neuromuscular electrical stimulation (NMES) in hemodialysis patients. Methods: We performed a 12-week, multicenter, randomized controlled trial. The participants were randomly assigned to the control group, the protein group (25 g of protein at every dialysis session), the NMES group (intradialytic...
- Erythropoiesis-stimulating agent responsiveness and hemoglobin variability is associated with fat tissue index
in hemodialysis patients with darbepoetin-alfa treatment: a prospective observational cohort study
- Hyokyeong Yu, Dong-Jin Oh, Do Hyoung Kim
- Kidney Res Clin Pract. 2025;44(2):299-309. Published online December 31, 2024
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Background: Although the introduction of erythropoietin-stimulating agents (ESAs) has led to better clinical outcomes in patients undergoing hemodialysis (HD), fluctuations in hemoglobin (Hb) levels, known as Hb variability, are frequently observed. However, only a few studies have evaluated the association between Hb variability and nutritional status in patients undergoing HD. Methods: In this prospective study conducted between March 1, 2020,...
- Target blood pressure in Korean hemodialysis patients for optimal survival
- Ji Eun Kim, Yun Jin Choi, Soon-Young Hwang, Hyeon Seok Hwang, Kyung Hwan Jeong, Eunjung Cho, Shin Young Ahn, Young Joo Kwon, Ju-Young Moon, Gang-Jee Ko
- Kidney Res Clin Pract. 2025;44(2):310-323. Published online November 1, 2023
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Background: Hypertension is a major cardiovascular risk factor in hemodialysis patients. This study identified the optimal blood pressure (BP) target for Korean hemodialysis patients using the Korean Renal Dialysis System (KORDS) dataset from the Korean Society of Nephrology and a pooled analysis for previous studies. Methods: Hemodialysis patients were classified according to their systolic (SBP) and diastolic BP (DBP) at...
- Sarcopenia is independently associated with mortality and recovery from dialysis in critically ill patients with sepsis-induced acute kidney injury receiving continuous renal replacement therapy
- Il Young Kim, Byung Min Ye, Seo Rin Kim, Dong Won Lee, Soo Bong Lee
- Kidney Res Clin Pract. 2025;44(2):324-337. Published online May 2, 2024
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Background: Sarcopenia upon admission to the intensive care unit (ICU) consistently correlates with adverse outcomes, including heightened mortality, in critically ill patients. This study aims to investigate the independent association of sarcopenia with both mortality and recovery from dialysis in critically ill patients with sepsis-induced acute kidney injury (SIAKI) undergoing continuous renal replacement therapy (CRRT). Methods: This retrospective study included...
- Immediate-start peritoneal dialysis without break-in-period: an 18-year retrospective cohort study on patient survival
- Jee Young Lee, Hyun-Jin Cho, Yoo-Sun Joo, Hye-Jin Na, Jung-Hwan Park, Young-Il Jo
- Kidney Res Clin Pract. 2025;44(2):338-348. Published online February 19, 2024
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Background: Immediate-start peritoneal dialysis (ISPD) is an effective renal replacement therapy that can prevent central venous catheterization due to its immediate initiation of peritoneal dialysis (PD) after catheter insertion without a break-in period. This study aimed to investigate the effect of ISPD on long-term patient survival. Methods: In this retrospective single-center cohort study, 178 consecutive patients who started PD from...
- Necessity of induction agent modification for old age kidney transplant recipients
- Kyeong Deok Kim, Kyo Won Lee, Jae Berm Park, Woo Sung Sim, Manuel Lim, Eun Sung Jeong, Jieun Kwon, Jaehun Yang
- Kidney Res Clin Pract. 2025;44(2):349-360. Published online November 1, 2023
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Background: Immunosenescence gradually deteriorates the function of the immune system, making elderly patients susceptible to infection, while reducing rejection of organ transplants. Therefore, age-adaptive immunosuppression is necessary in the elderly. We evaluated clinical outcomes such as rejection and infection rate when using basiliximab and rabbit anti-thymocyte globulin (r-ATG) as induction agents in elderly and young organ transplant recipients. Methods: We...
- The impact of donor hepatitis B virus infection on transplant outcomes in deceased donor kidney transplantation recipients
- You Luo, Rui Zhang, Xiao Hu, Zuofu Tang, Jinhua Zhang, Jiaqing Wu, Ning Na, Hengjun Xiao
- Kidney Res Clin Pract. 2025;44(2):361-375. Published online July 24, 2024
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Background: The use of hepatitis B virus (HBV)-positive donor kidneys to expand the donor pool has been implemented, but limited evidence exists regarding their impact on transplant outcomes. This study aimed to investigate the effects of donor HBV infection on transplant outcomes. Methods: Donor and recipient data between 2015 and 2021 were collected. A total of 743 kidney transplant cases...
- Longitudinal progression trajectory of estimated glomerular filtration rate in children with chronic kidney disease: results from the KNOW-Ped CKD (KoreaN cohort study for Outcomes in patients With Pediatric Chronic Kidney Disease)
- Eun Mi Yang, Jayoun Kim, Eujin Park, Kyoung Hee Han, Seong Heon Kim, Heeyeon Cho, Jae Il Shin, Min Hyun Cho, Joo Hoon Lee, Ji Hyun Kim, Hee Gyung Kang, Il-Soo Ha, Yo Han Ahn
- Kidney Res Clin Pract. 2025;44(2):376-388. Published online February 23, 2024
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Background: The natural course of chronic kidney disease (CKD) progression in children varies according to their underlying conditions. This study aims to identify different patterns of subsequent decline in kidney function and investigate factors associated with different patterns of estimated glomerular filtration rate (eGFR) trajectories. Methods: We analyzed data from the KNOW-Ped CKD (KoreaN cohort study for Outcomes in patients...
- Long-term outcomes and associated prognostic risk factors of childhood-onset lupus nephritis
- Eujin Park, Jiwon Jung, Jeesu Min, Hyeonju Lee, Min Ji Park, Ji Yeon Song, Ji Hyun Kim, Kyung Mi Jang, Eun Mi Yang, Yo Han Ahn, Min Hyun Cho, Joo Hoon Lee, Young Seo Park, Soon Chul Kim, Se Jin Park, Jung Won Lee, Kee Hyuck Kim, Ki Soo Pai, Hee Gyung Kang, Seong Heon Kim
- Kidney Res Clin Pract. 2025;44(2):389-395. Published online December 18, 2023
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Background: This study investigated the clinical characteristics and kidney outcomes of childhood-onset lupus nephritis (LN), and risk factors associated with prognosis. Methods: We enrolled 216 patients with histologically diagnosed LN during childhood. The Korean Society of Pediatric Nephrology organized a retrospective cohort study of childhood-onset LN in 13 major pediatric nephrology centers in South Korea. Results: The mean age at...
- Images in Practice
- Diffuse subcutaneous oxalosis masquerading as lower limb cellulitis
- Gerry George Mathew, Anand Alwan
- Kidney Res Clin Pract. 2025;44(2):396-397. Published online January 17, 2025
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