-
Editorial
May 31, 2023
- Primary cilia of the kidney: from ciliopathy to urinary concentration
- Gheun-Ho Kim
- Kidney Res Clin Pract. 2023;42(3):279-281.
- Editorial
- Primary cilia of the kidney: from ciliopathy to urinary concentration
- Gheun-Ho Kim
- Kidney Res Clin Pract. 2023;42(3):279-281. Published online May 31, 2023
-
- A novel strategy employing the flavonoid fisetin to halt the progression of renal fibrosis in obstructive nephropathy
- Tae-Hwan Kwon
- Kidney Res Clin Pract. 2023;42(3):282-285. Published online May 31, 2023
-
- Review Article
- Acute kidney injury in patients with acute-on-chronic liver failure: clinical significance and management
- Jeong-Ju Yoo, Moo Yong Park, Sang Gyune Kim
- Kidney Res Clin Pract. 2023;42(3):286-297. Published online May 22, 2023
-
Acute-on-chronic-liver failure (ACLF) refers to a phenomenon in which patients with chronic liver disease develop multiple organ failure due to acute exacerbation of underlying liver disease. More than 10 definitions of ACLF are extant around the world, and there is lack of consensus on whether extrahepatic organ failure is a main component or a consequence of ACLF. Asian and European...
- Expanding the potential therapeutic options of hemoperfusion in the era of improved sorbent biocompatibility
- Aikaterini Damianaki, Emelina Stambolliu, Zoi Alexakou, Dimitrios Petras
- Kidney Res Clin Pract. 2023;42(3):298-311. Published online March 29, 2023
-
Hemoperfusion has been considered a promising adjuvant treatment for chronic diseases and some acute states when specific removal of pathogenic factors from the bloodstream is desired. Over the years, advances in adsorption materials (e.g., new synthetic polymers, biomimetic coating, and matrixes with novel structures) have renewed scientific interest and expanded the potential therapeutic indications of hemoperfusion. There is growing evidence...
- Original Article
- Shortening of primary cilia length is associated with urine concentration in the kidneys
- Min Jung Kong, Sang Jun Han, Sung Young Seu, Ki-Hwan Han, Joshua H. Lipschutz, Kwon Moo Park
- Kidney Res Clin Pract. 2023;42(3):312-324. Published online May 31, 2023
-
Background: The primary cilium, a microtubule-based cellular organelle present in certain kidney cells, functions as a mechano-sensor to monitor fluid flow in addition to various other biological functions. In kidneys, the primary cilia protrude into the tubular lumen and are directly exposed to pro-urine flow and components. However, their effects on urine concentration remain to be defined. Here, we investigated...
- The flavonoid fisetin ameliorates renal fibrosis by inhibiting SMAD3 phosphorylation, oxidative damage, and inflammation in ureteral obstructed kidney in mice
- Ha Young Ju, Jongwan Kim, Sang Jun Han
- Kidney Res Clin Pract. 2023;42(3):325-339. Published online March 22, 2023
-
Background: Renal fibrosis is characterized by the accumulation of extracellular matrix and inflammatory cells and kidney dysfunction, which is a major pathway in the progression of chronic kidney disease (CKD). Accumulating evidence indicates that oxidative stress plays a critical role in the initiation and progression of CKD via proinflammatory and profibrotic signaling pathways. Fisetin (3,3′,4′,7-tetrahydroxyflavone) has biological activities including antioxidant,...
- Body water percentage from childhood to old age
- Hong Lu, Eric Ayers, Pragnesh Patel, Tej K. Mattoo
- Kidney Res Clin Pract. 2023;42(3):340-348. Published online May 16, 2023
-
Background: Total body water (TBW) increases with growth, but the body water percentage (TBW%) decreases with aging. The objective of our study was to delineate TBW% in males and females by bioelectrical impedance analysis (BIA) from early childhood to old age. Methods: We enrolled 545 participants aged 3 to 98 years (258 male, 287 female). Among the participants, 256 had...
- Clinical characteristics of acute kidney injury in patients with glyphosate surfactant herbicide poisoning
- A Young Cho, Ju Hwan Oh, Sung Sik Oh, Kwang Young Lee, In O Sun
- Kidney Res Clin Pract. 2023;42(3):349-357. Published online April 6, 2023
-
Background: In this study, we investigated the clinical characteristics of acute kidney injury (AKI) in patients with glyphosate surfactant herbicide (GSH) poisoning. Methods: This study was performed between 2008 and 2021 and included 184 patients categorized into the AKI (n = 82) and non-AKI (n = 102) groups. The incidence, clinical characteristics, and severity of AKI were compared between the groups...
- Risk factors for post-contrast acute kidney injury in patients sequentially administered iodine- and gadolinium-based contrast media on the same visit to the emergency department: a retrospective study
- Changshin Kang, Soo Hyun Han, Jung Soo Park, Dae Eun Choi
- Kidney Res Clin Pract. 2023;42(3):358-369. Published online April 26, 2023
-
Background: This study compares the incidence of post-contrast acute kidney injury (PC-AKI) in patients who received a single administration of iodine-based contrast medium (ICM) with that in patients who received a sequential administration of ICM and gadolinium- based contrast agents (GBCA) in a single visit to an emergency department (ED) to determine the risk factors for PC-AKI. Methods: Patients who...
- Risk of ventricular tachycardia and its outcomes in patients undergoing continuous renal replacement therapy due to acute kidney injury
- Seong Geun Kim, Donghwan Yun, Jayoun Kim, Jinwoo Lee, Min Woo Kang, Yong Chul Kim, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Hoseok Koo, Yon Su Kim, Seung Seok Han
- Kidney Res Clin Pract. 2023;42(3):370-378. Published online March 22, 2023
-
Background: Despite efforts to treat critically ill patients who require continuous renal replacement therapy (CRRT) due to acute kidney injury (AKI), their mortality risk remains high. This condition may be attributable to complications of CRRT, such as arrhythmias. Here, we addressed the occurrence of ventricular tachycardia (VT) during CRRT and its relationship with patient outcomes. Methods: This study retrospectively enrolled...
- Dialysis specialist care and patient survival in hemodialysis facilities: a Korean nationwide cohort study
- Hayne Cho Park, Do Hyoung Kim, Ajin Cho, Young Eun Kwon, Dong-Ryeol Ryu, Jinseog Kim, Ki Hwa Yang, Ji Hyeon Shin, Eun Jung Son, Young-Ki Lee
- Kidney Res Clin Pract. 2023;42(3):379-388. Published online March 22, 2023
-
Background: It is important for the dialysis specialist to provide essential and safe care to hemodialysis (HD) patients. However, little is known about the actual effect of dialysis specialist care on the survival of HD patients. We therefore investigated the influence of dialysis specialist care on patient mortality in a nationwide Korean dialysis cohort. Methods: We used an HD quality assessment...
- A non-muscle myosin heavy chain 9 genetic variant is associated with graft failure following kidney transplantation
- Felix Poppelaars, Siawosh K. Eskandari, Jeffrey Damman, Marc A. Seelen, Bernardo Faria, Mariana Gaya da Costa
- Kidney Res Clin Pract. 2023;42(3):389-402. Published online May 22, 2023
-
Background: Despite current matching efforts to identify optimal donor-recipient pairs for kidney transplantation, alloimmunity remains a major source of late transplant failure. Additional genetic parameters in donor-recipient matching could help improve long-term outcomes. Here, we studied the impact of a non-muscle myosin heavy chain 9 gene (MYH9) polymorphism on allograft failure. Methods: We conducted an observational cohort study, analyzing the DNA...
- Images in Practice
- Zebra bodies in lupus nephritis after hydroxychloroquine therapy
- Anshima Singh, Vinita Agrawal
- Kidney Res Clin Pract. 2023;42(3):403-404. Published online May 11, 2023
-
- Correspondence
- Acquired antineutrophil cytoplasmic antibody-associated glomerulonephritis after COVID-19 infection
- Jeong-Yeun Lee, Hyeon Seok Hwang
- Kidney Res Clin Pract. 2023;42(3):405-408. Published online April 14, 2023
-
