Korean Journal of Nephrology 1996;15(1):39-44.
영아기 신증후군의 임상적 고찰
이상훈 , 박성근 , 차성호 , 조병수 , 양문호 , 고영태 , 조성윤
Abstract
We performed clinical observation on infantile nephrotic syndrome in 9 cases which were managed in the department of pediatrics at Kyung Hee University Hospital from Jan. 1980 to Jan. 1995. The results were as follows ', 1) The mean age of infantile nephrotic syndrome were 5.9 months, and male to female ratio was 1.25:1. 2) The etiologic classification was Finnish type in 2, French type in 1, congenital syphilitis in 2, renal vein thrombosis(RVT) in 1 and MCNS in 3 cases. 3) Among 9 cases, 8 showed microscopic hematuria. 4) As for the effect of treatment and prognosis, all 2 Finnish type and one French type patients who were treated with supportive therapy died at 2, 10, and 16 months, respectively. And all others were recovered by proper treatment with penicillin, dipyridamole, and prednisolone, respectively. In conclusion, correct and early diagnosis is very important for the proper therapy and better pro- gnosis because congenital nepnrotic syndrome developed before the first 6 months of life had a poor prognosis except the secondary ones. And infantile nephrotic syndrome after 6 months of life, except French type, was steroid sensitive minial change nephrotic syndrome, in our cases.
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