Korean Journal of Nephrology 1998;17(6):978-982.
무증상 단백뇨로 나타난 막성 신병증과 동반된 조기위암 1예 (A Case of Membranous Nephropathy Improved by Removal of Early Gastric Cancer)
우창근, 서경희, 신경순, 이덕현, 이동엽, 제석준, 황중하, 이중기, 김익수, 김용진 (Chang Keun Woo, Kyung Hee Suh, Kyung Soon Shin, Duk Hyun Lee, Dong Yeup Lee, Suk Joon Je, Joong Ha Hwang, Choong Ki Lee, Ik Soo Kim and Yong Jin Kim)
Abstract
The nephrotic syndrome in association with extrarenal malignancy is not an uncommon event. The membranous nephropathy is most frequently associated with various carcinomas of the lung, breast, stomach and colon. Though the exact causal relationship has not been determined completely, deposition of the immune complexes composed of antitumor antibody and tumor antigens in the subepithelium is most favorably accepted. We experienced a patient with previously diagnosed membranous nephropathy and subsequently demonstrated early gastric cancer during patient follow-up. After surgical resection proteinuria improved significantly. All physicians are strongly recommended to examine thoroughly and search carefully for possibility of concomitant occult malignancy when an aged patient, especially over 40 years old, is diagnosed as a nephrotic syndrome.
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