Korean Journal of Nephrology 1998;17(1):128-133.
과칼슘뇨증을 동반한 신성 저요산혈증 1예
서기현 , 배상수 , 박상준 , 김혜영 , 허우성 , 이윤하 , 김윤구 , 오하영
Abstract
We encountered a case of renal hypouricemia and absorptive hypercalciuria. Although renal hypourice- mia is asymptomatic as usual, it is rarely comp- licated with acute renal failure and urolithiasis. A 43-year-old man had hypouricemia (serum uric acid, 0.6-1.0mg/dl) with an increased renal uric acid clea- rance (69.4ml/min), hypercalciuria (367.2mg/day). In present case, there was no response of uric acid excretion to either pyrazinamide or probenecid and hypercalciuria disappeared after calcium restriction diet. These results suggest that the present case had the defect of both pre-and postsecretory reabso- rption of uric acid and absorptive hypercalciuria.
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