Korean Journal of Nephrology 1998;17(1):134-139.
본드 흡입 후에 진단된 원위 신세뇨관성 산증 1예
마경애 , 이선민 , 정성철 , 김상돈 , 임현이 , 신규태 , 김흥수 , 김도헌 , 김진 , 한진석
Abstract
We describe a case of distal renal tubular acidosis in a 20-year-old woman with a history of glue sniffing. On admission she complained of nausea and somnolence. Severe hypokalemia and hyperchloremic metabolic acidosis with normal anion gap were noted. Her urinary osmolar gap and anion gap results were consistent with presence of renal tubular acidosis. Bicarbonate loading test along with urine PCOz confirmed that she had type 1 renal tubular acidosis due to hydrogen ion secretion defect. Immunohistochemical staining of renal biopsy specimen with anti H'-ATPase antibody showed absence of proton pump in the collecting duct. Thus a case of distal renal tubular acidosis in association with glue sniffing is reported with a review of literatures.
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