Korean Journal of Nephrology 1999;18(4):644-647.
완전 포기상태에 동반된 신증후군 1예 (A Case of Nephrotic Syndrome Associated with Total Hydatidiform Mole)
김희중, 권영은, 윤상준, 손현화, 김종오, 임성철, 정종훈 (Hee Joong Kim, Yong Eun Kwon, Sang Jun Youn, Hyun Hwa Sohn, Jong O Kim, Sung Chul Lim and Jong Hoon Chung)
Abstract
A case study and review of nephrotic syndrome associated with a total Hydatidiform mole in 54- year-old female is presented. She has generalized edema, nephrotic range proteinuria(8.05gm/day), hypoalbuminemia(2.5g/dl) and high serum level of beta- hCG(200,000IU/L). Radiological investigations showed a 16-cm sized heterogenous enhanced mass in the uterus. A renal biopsy performed before evacuation of H-mole showed a focal segmental glomerulosclerosis. The complete remission of symptoms and signs of the nephrotic syndrom after evacuation of a molar tissue was achieved. A review of the literature revealed that this patient appears to be the first case of the FSGS with nephrotic syndrome associated with a total mole that remitted completely after the mole evacuation.
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