Korean Journal of Nephrology 2001;20(5):916-921.
증례 : 신증후군에 합병된 다발성 혈전증에 대한 MRA 진단 및 성공적인 혈전 용해술 1 예 (Case Reports : A Magnetic Resonance Angiographic Diagnosis and Successful Thrombolytic Therapy in The Thrombosis of Renal Vein Complicated from Nephroitc Syndrome)
최성철(Sung Chul Choi),허우성(Woo Seong Huh),도정호(Jung Ho Do),김정아(Jung Ah Kim),한혁준(Hyeok Jun Han),정시정(Shi Jung Chung),박진아(Jin Ah Park),김윤구(Yoon Goo Kim),김대중(Dae Joong Kim),오하영(Ha Young Oh),김보현(Bo Hyun Kim)
Abstract
The nephrotic syndrome has been considered a hypercoagulable state since it may be complicated by thromboembolic events of the venous or the arterial circulations. Diverse pathogenetic factors leading to the hypercoagulable state in nephrotic syndrome have been recognized. Renal vein thrombosis is a serious complication, which might lead to either renal failure or to secondary thromboembolic processes like pulmonary thromboembolism. Although it may present acutely with flank pain and macroscopic hematuria, the majority of cases run an indolent course. Until relatively recently, the diagnosis could only be confidently confirmed or excluded with selective renal venography but, more recently, computerized tomography and magnetic resonance imaging have been used. Anticoagulant therapy with heparin and warfarin apparently halts the natural progression of the disease and allowing for slow recovery. The possibility of more rapid and complete resolution with thrombolytic agents warranted their application. We described a case of bilateral renal vein thrombosis diagnosed by the new technique of magnetic resonance angiography and successful treatment by thrombolytic agent.
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