Korean Journal of Nephrology 2011;30(5):561-564.
A Case of Trichosporon inkin Continuous Ambulatory Peritoneal Dialysis Peritonitis Identified by 18S rRNA Sequencing
Hee Seung Lee, M.D.1, Jae Hyun Choi, M.D.1, Sun Moon Kim, M.D.1, Young Kwang Shim, M.D.1, Mun Hyuk Seong, M.D.1, Hye-young Kim, M.D.1, Kyeong Seob Shin, M.D.2 and Soon Kil Kwon, M.D.1
Renal Division1 and Laboratory Medicine2
College of Medicine, Chungbuk National University, Cheongju Korea
증례 : A Case of Trichosporon inkin Continuous Ambulatory Peritoneal Dialysis Peritonitis Identified by 18S rRNA Sequencing
Hee Seung Lee, M.D.1, Jae Hyun Choi, M.D.1, Sun Moon Kim, M.D.1, Young Kwang Shim, M.D.1, Mun Hyuk Seong, M.D.1, Hye-young Kim, M.D.1, Kyeong Seob Shin, M.D.2 and Soon Kil Kwon, M.D.1
Renal Division1 and Laboratory Medicine2, College of Medicine, Chungbuk National University, Cheongju Korea
Abstract
Fungal peritonitis in peritoneal dialysis patients is hard to treat without catheter removal and shows higher mortality. Although Candida species is the most common pathogen of fungal peritonitis, there are few reports about Trichosporon inkin induced peritonitis. The authors report the first case of Trichosporon induced peritonitis identified by 18S rRNA sequencing. A 52-year-old male presented to emergency room due to generalized abdominal pain. He had been on continuous ambulatory peritoneal dialysis for 3 years because of end stage renal disease caused by diabetic kidney disease. Dialysate white blood cell count was 800/mL3 with 77% of neutrophils and culture showed Trichosporon inkin via Vitek II system. With removal of catheter and treatment of antifungal agent, the patient was fully recovered and stable on hemodialysis. In case of immunocompromised dialysis patients, uncommon fungal pathogens should be taken into considerations.
Key Words: Peritoneal dialysis, Peritonitis, Trichosporon inkin, 18S ribosomal RNA


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