Editorial

November 30, 2022


A troubled mind troubles the kidney: a brain-to-kidney axis?
Keun You Kim, Eosu Kim
Kidney Res Clin Pract. 2022;41(6):637-639.

Editorial

November 28, 2022


The effects of nitric oxide and 8-iso-prostaglandin F2α on chloride absorption in cortical thick ascending limb
Tae-Hwan Kwon
Kidney Res Clin Pract. 2022;41(6):640-643.

Review Article

October 25, 2022


Healthy aging and chronic kidney disease
Reshma Aziz Merchant, Anantharaman Vathsala
Kidney Res Clin Pract. 2022;41(6):644-656.

Review Article

January 21, 2022


Nutrition and quality of life in chronic kidney disease patients: a practical approach for salt restriction
Kunitoshi Iseki
Kidney Res Clin Pract. 2022;41(6):657-669.

Review Article

February 22, 2022


Why should we focus on high-volume hemodiafiltration?
Sug-Kyun Shin, Young-Il Jo
Kidney Res Clin Pract. 2022;41(6):670-681.

Review Article

July 19, 2022


Advances in the management of diabetic kidney disease: beyond sodium-glucose co-transporter 2 inhibitors
Anthony T. P. Chan, Sydney C. W. Tang
Kidney Res Clin Pract. 2022;41(6):682-698.

Original Article

August 17, 2022


Nitric oxide-inhibited chloride transport in cortical thick ascending limbs is reversed by 8-iso-prostaglandin-F2α
Pablo D. Cabral, Guillermo B. Silva, Sandra T. Baigorria, et al.
Kidney Res Clin Pract. 2022;41(6):699-706.

Original Article

July 19, 2022


Clinical relevance of postoperative proteinuria for prediction of early renal outcomes after kidney transplantation
Junseok Jun, Kyungho Park, Hyun Suk Lee, et al.
Kidney Res Clin Pract. 2022;41(6):707-716.

Original Article

July 19, 2022


Hospital mortality and prognostic factors in critically ill patients with acute kidney injury and cancer undergoing continuous renal replacement therapy
Da Woon Kim, Geum Suk Jang, Kyoung Suk Jung, et al.
Kidney Res Clin Pract. 2022;41(6):717-729.

Original Article

June 20, 2022


Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression
Hyunsuk Kim, Jinmo Sung, Ju Young Bae, et al.
Kidney Res Clin Pract. 2022;41(6):730-740.

Original Article

July 19, 2022


Association of sarcopenia and its components with clinical outcomes in patients undergoing peritoneal dialysis
Seok Hui Kang, A Young Kim, Jun Young Do
Kidney Res Clin Pract. 2022;41(6):741-752.

Original Article

September 8, 2022


Associations among Alzheimer disease, depressive disorder, and risk of end-stage kidney disease in elderly people
Shin Chan Kang, Hee Byung Koh, Hyung Woo Kim, et al.
Kidney Res Clin Pract. 2022;41(6):753-763.

Correspondence

November 16, 2022


Successful provision of hemodialysis to patients with confirmed COVID-19 in Korea: the role of a cooperative network between public and private medical systems
Ji-Young Choi, Jeong-Hoon Lim, Seungyeup Han, et al.
Kidney Res Clin Pract. 2022;41(6):764-767.

Correspondence

November 29, 2022


Treatment of acute tacrolimus toxicity with phenytoin after Paxlovid (nirmatrelvir/ritonavir) administration in a kidney transplant recipient
Eun-Jeong Kwon, Gi-Ae Yun, Seokwoo Park, et al.
Kidney Res Clin Pract. 2022;41(6):768-770.

Review Articles
Pleotropic effects of hypoxia-inducible factor-prolyl hydroxylase domain inhibitors: are they clinically relevant?
Yu-Hsiang Chou, Szu-Yu Pan, Shuei-Liong Lin
Received June 6, 2022  Accepted June 30, 2022  
Anemia is common in patients with chronic kidney disease (CKD) and is mainly caused by insufficient production of erythropoietin from fibrotic kidney. Because anemia impairs quality of life and overall prognosis, recombinant human erythropoietin-related products (erythropoiesis-stimulating agents, ESAs) have been developed to increase hemoglobin level for decades. However, many safety concerns have been announced regarding the use of ESAs, including...
DOI: https://doi.org/10.23876/j.krcp.22.118    [Epub ahead of print]
Recent innovations in renal replacement technology and potential applications to transplantation and dialysis patients: a review of current methods
Calista L Dominy, Ethan B. Shamsian, Kennedy E. Okhawere, Talia G. Korn, Kirolos Meilika, Ketan Badani
Received April 11, 2022  Accepted May 30, 2022  
The current standard of care for patients with end-stage renal disease (ERSD) is a kidney transplant or dialysis when a donor organ is not available. The growing gap between patients who require a kidney transplant and the availability of donor organs as well as the negative effects of long-term dialysis, such as infection, limited mobility, and risk of cancer development,...
DOI: https://doi.org/10.23876/j.krcp.22.074    [Epub ahead of print]
Recent advances in electron microscopy for the diagnosis and research of glomerular diseases
Kazuho Honda, Takashi Takaki, Dedong Kang
Received November 19, 2021  Accepted December 26, 2021  
Recent technical advances in the detection of backscattered electrons during scanning electron microscopy (SEM) have improved resolution and have provided several new technologies for research and clinical practice in kidney disease. The advances include three-dimensional (3D) electron microscopy (3D-EM), correlative light and electron microscopy (CLEM), low-vacuum SEM (LVSEM), and scanning transmission electron microscopy (STEM). 3D-EM analysis used to be laborious,...
DOI: https://doi.org/10.23876/j.krcp.21.270    [Epub ahead of print]
Uremic pruritus: pathophysiology, clinical presentation, and treatments
Mei-Ju Ko, Yu-Sen Peng, Hon-Yen Wu
Received August 30, 2021  Accepted December 25, 2021  
Uremic pruritus is one of the most common and bothersome symptoms in patients with end-stage renal disease. Most patients with uremic pruritus experience a prolonged and relapsing course and significant impairments of quality of life. The pathophysiology of uremic pruritus is not completely understood. A complex interplay among cutaneous biology and the nervous and immune systems has been implicated, with...
DOI: https://doi.org/10.23876/j.krcp.21.189    [Epub ahead of print]
Original Articles
Serum calcification propensity and its association with biochemical parameters and bone mineral density in hemodialysis patients
Hyunsook Kim, Ae Jin Kim, Han Ro, Jae Hyun Chang, Hyun Hee Lee, Wookyung Chung, Ji Yong Jung
Received March 29, 2022  Accepted June 3, 2022  
Background: T50 is a novel serum-based marker that assesses the propensity for calcification in serum. A shorter T50 indicates a greater propensity to calcify and has been associated with cardiovascular disease and mortality among patients with chronic kidney disease. The factors associated with T50 and the correlation between T50 and bone mineral density (BMD) are unknown in hemodialysis (HD) patients. Methods:...
DOI: https://doi.org/10.23876/j.krcp.22.059    [Epub ahead of print]
Impact of needle type on substitution volume during online hemodiafiltration: plastic cannulae versus metal needles
AJin Cho, Hayne Cho Park, Do Hyoung Kim, Han Byul Choi, Gi Hyun Song, Hyunsuk Kim, Seok-hyung Kim, Gwangho Choi, Jwa-Kyung Kim, Young Rim Song, Jong-Woo Yoon, Young-Ki Lee
Received November 25, 2021  Accepted May 17, 2022  
Background: Plastic cannulae have attracted increasing interest as an alternative to traditional metal needles with the aim of reducing cannulation-related complications. We investigated whether the substitution volumes during hemodiafiltration differ using these two types of needles in dialysis patients. Methods: An intervention study involving 26 hemodialysis patients was conducted in Korea between March and September in 2021. Patients first received online...
DOI: https://doi.org/10.23876/j.krcp.21.281    [Epub ahead of print]
Optimal peritoneal fluid white blood cell count for diagnosis of peritonitis in peritoneal dialysis patients
Margarita Kunin, Sharon Mini, Nabil Abu-Amer, Pazit Beckerman
Received October 29, 2021  Accepted May 7, 2022  
Background: The diagnosis of peritonitis among peritoneal dialysis (PD) patients is based on clinical presentation, dialysis effluent white blood cell (WBC) count, and dialysis effluent culture. Peritoneal fluid WBC count is very important in the initial diagnosis of peritonitis. The purpose of this work was to determine the optimal number of peritoneal WBCs with different clinical presentations at admission to...
DOI: https://doi.org/10.23876/j.krcp.21.254    [Epub ahead of print]
Hemodialysis facility star rating affects mortality in chronic hemodialysis patients: a longitudinal observational cohort study
Hayne Cho Park, Hyung Yun Choi, Do Hyoung Kim, AJin Cho, Young Eun Kwon, Dong-Ryeol Ryu, Ki Hwa Yang, Eun Mi Won, Ji Hyeon Shin, Jinseog Kim, Young-Ki Lee
Received February 22, 2022  Accepted May 16, 2022  
Background: Many countries have their own hemodialysis (HD) quality assurance programs and star rating systems for HD facilities. However, the effects of HD quality assurance programs on patient mortality are not well understood. Therefore, in the present study, the effects of the Korean HD facility star rating on patient mortality in maintenance HD patients were evaluated. Methods: This longitudinal, observational...
DOI: https://doi.org/10.23876/j.krcp.22.039    [Epub ahead of print]
Deep learning predicts the differentiation of kidney organoids derived from human induced pluripotent stem cells
Keonhyeok Park, Jong Young Lee, Soo Young Lee, Iljoo Jeong, Seo-Yeon Park, Jin Won Kim, Sun Ah Nam, Hyung Wook Kim, Yong Kyun Kim, Seungchul Lee
Received January 27, 2022  Accepted May 2, 2022  
Background: Kidney organoids derived from human pluripotent stem cells (hPSCs) contain multilineage nephrogenic progenitor cells and can recapitulate the development of the kidney. Kidney organoids derived from hPSCs have the potential to be applied in regenerative medicine as well as renal disease modeling, drug screening, and nephrotoxicity testing. Despite biotechnological advances, individual differences in morphological and growth characteristics among kidney...
DOI: https://doi.org/10.23876/j.krcp.22.017    [Epub ahead of print]
Weight change and risk of depression in patients with diabetic kidney disease: a nationwide population-based study
Hong Sang Choi, Bongseong Kim, Kyung-Do Han, Tae Ryom Oh, Sang Heon Suh, Minah Kim, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Received December 8, 2021  Accepted May 10, 2022  
Background: Several studies have reported that depression is prevalent in patients with diabetes or chronic kidney disease. However, the relationship between weight changes and the risk of depression has not been elucidated in patients with diabetic kidney disease (DKD). Methods: From the Korean National Health Insurance Service database, we selected 67,866 patients with DKD and body weight data from two...
DOI: https://doi.org/10.23876/j.krcp.21.294    [Epub ahead of print]
Distribution of pathological types and epidemiological characteristics based on kidney biopsy in Northwest China
Yunlong Qin, Jin Zhao, Xiao Wei, Yuwei Wang, Zixian Yu, Yumeng Zhang, Shiren Sun
Received December 13, 2021  Accepted May 6, 2022  
Background: The spectrum of biopsy-confirmed kidney disease varies with regions and periods. We describe the distribution of pathological types and epidemiological characteristics of kidney diseases in Northwest China due to regional differences in geographical environment, social economy, and dietary habits. Methods: Kidney biopsy cases from 2005 to 2020 in Xijing Hospital were retrospectively analyzed. Pathological characteristics of patients in different...
DOI: https://doi.org/10.23876/j.krcp.21.296    [Epub ahead of print]

Kidney Research
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